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Anticholinergic chronotropic agents are also known as muscarinic antagonists or parasympatholytic. All of them are competitive antagonists, and selectively block the effects of parasympathetic nerve activity. They block cardiac muscarinic receptors and cause tachycardia. They also have effect on other body systems such as inhibition of secretions, dilatation of pupils in the eyes, slowed gastrointestinal motility and relaxation of smooth muscle in lungs, urinary tract, etc.

Anticholinergic chronotropic agents are used to treat atrioventricular heart block and bradycardia.