Ciprofloxacin is a fluoroquinolone (flor-o-KWIN-o-lone) antibiotic that fights bacteria in the body.

Ciloxan (for use in the eyes) is used to treat bacterial infections of the eyes.

Ciloxan is also used to treat an ulcer in the cornea of the eye.

Ciprofloxacin will not treat a viral or fungal infection of the eye. Ciloxan is for use in treating only bacterial infections.

Ciloxan may also be used for purposes not listed in this medication guide.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

While treating a corneal ulcer, you may notice a whitish buildup in your eye. This is a sign that the medication is working and is not a harmful effect. This buildup should clear within a few days or weeks of treatment.

If you wear contact lenses, remove them before applying Ciloxan. Ask your doctor if contact lenses can be reinserted after application of the medication.

Wash your hands before using eye medication.

To apply the eye drops:

• Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.

• Close your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.

• Use only the number of drops your doctor has prescribed. If you use more than one drop, wait about 5 minutes between drops.

• Wait at least 10 minutes before using any other eye drops your doctor has prescribed.

To apply the ointment:

• Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the ointment tube with the tip pointing toward this pocket. Look up and away from the tip.

• Squeeze out a ribbon of ointment into the lower eyelid pocket without touching the tip of the tube to your eye. Blink your eye gently and then keep it closed for 1 or 2 minutes.

• Use a tissue to wipe excess ointment from your eyelashes.

• After opening your eyes, you may have blurred vision for a short time. Avoid driving or doing anything that requires you to be able to see clearly.

Do not touch the tip of the eye dropper or ointment tube or place it directly on your eye. A contaminated tip can infect your eye, which could lead to serious vision problems.

Ciloxan is most often used for 5 to 14 days in a row. Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.

Store at room temperature away from moisture, heat, and light. Do not freeze. Keep the bottle or tube tightly closed when not in use.

You should not use Ciloxan if you are allergic to ciprofloxacin or other fluoroquinolones (gemifloxacin, levofloxacin, moxifloxacin, ofloxacin, norfloxacin, and others).

Do not use this medicine to treat a viral or fungal infection in the eye. Ciloxan is for use in treating only bacterial infections of the eye.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether ciprofloxacin ophthalmic passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

Ciprofloxacin eye drops (solution) are not approved for use by anyone younger than 1 year old. Ciprofloxacin ointment is not approved for use by anyone younger than 2 years old.

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

An overdose of Ciloxan is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

Avoid wearing contact lenses until you no longer have symptoms of the eye infection.

Ciloxan may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Do not use other eye medications unless your doctor tells you to.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Ciloxan may cause serious side effects. Call your doctor at once if you have:

• severe burning, stinging, or irritation after using this medicine; or

• eye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection).

Common side effects of Ciloxan may include:

• dry eyes or watery eyes;

• eye pain or discomfort;

• red or puffy eyelids;

• feeling like something is in your eye;

• blurred vision; or

• mild itching, redness, or other irritation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.