Alzheimer's: Excessive artificial light at night may increase risk

Evan Walker
Evan Walker TheMediTary.Com |
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New research finds a link between light pollution and Alzheimer’s disease. JodiJacobson/Getty Images
  • Excessive exposure to light pollution at night may raise the risk of developing Alzheimer’s disease.
  • Researchers found that in people 65 and younger light pollution had a stronger correlation to Alzheimer’s disease prevalence than any other risk factor studied.
  • Experts say more research is needed to fully determine if light pollution is a risk factor for Alzheimer’s disease.

Excessive light pollution at night could increase the risk of Alzheimer’s disease, particularly for people under 65.

Research published in Frontiers in Neuroscience found exposure to light pollution at night time could be an important modifiable risk factor to investigate in Alzheimer’s disease.

“We show that in the U.S. there is a positive association between [Alzheimer’s] prevalence and exposure to light at night, particularly in those under the age of 65,” Robin Voigt-Zuwala, Ph.D., first author of the study and an associate professor at Rush University Medical Center

“Nightly light pollution – a modifiable environmental factor – may be an important risk factor for [Alzheimer’s],” he said.

In undertaking their research, the study authors used data from satellites to determine the average night-time light intensity in the U.S. between the years 2012–2018.

They ranked the lower 48 U.S. states according to their average nighttime light intensity. The states were then split into five groups, from the darkest states at night with the lowest average light intensity to the brightest states at night with the highest average light intensity.

The researchers also gathered Medicare data to determine the prevalence of Alzheimer’s disease in those states.

They found statistical differences between the states that were the darkest at night and the brightest at night. Higher intensity of light pollution at night was positively associated with the prevalence of Alzheimer’s disease.

That effect held for people under and over the age of 65, for both men and women and for all races studied except for Asian Pacific Islanders.

They found that for people who were ages 65 and older, the prevalence of Alzheimer’s disease had a stronger correlation with nighttime light pollution than other potential disease risk factors like chronic kidney disease, alcohol abuse, depression, and obesity.

But for this group, there were some risk factors that had a stronger correlation with Alzheimer’s disease than light pollution. These included high blood pressure, diabetes, and stroke.

In people aged under 65, the study authors found that a higher intensity of light pollution at night was associated with a greater prevalence of Alzheimer’s disease than any other risk factor studied.

The study authors note their research has some limitations. The Medicare data was limited, the study examined prevalence of Alzheimer’s but not incidence and no indoor light data was available.

“Indoor light exposure (e.g., televisions, computers, phones) is critically important and should be evaluated in future studies,” the study authors write. “The totality of outdoor and indoor nighttime light exposure is important to consider to fully understand the impact of nighttime light on [Alzheimer’s].”

Nikki-Anne Wilson, Ph.D., a University of New South Wales Postdoctoral Research Fellow and Conjoint Postdoctoral Research Fellow at Neuroscience Research Australia (NeuRA), who was not involved in the study, said that while it remains to be seen if nighttime light exposure is truly a risk factor for Alzheimer’s, sleep may be an important piece of the puzzle.

“Research investigating dementia, and factors which contribute to its development, is continuing to evolve as we address emerging issues in our environment. It is too early to say whether light pollution may contribute to dementia risk. However, we do know that the development of good sleep habits is associated with broader health benefits,” she told Medical News Today.

“Things like limiting screen time before bed, using curtains to shut out external light where possible, and maintaining a consistent sleep schedule are simple ways to improve sleep. Importantly, if you are experiencing considerable daytime sleepiness or symptoms of a sleep disorder, it is always best to get checked by your doctor.”
— Nikki-Anne Wilson

The researchers note there are numerous potential mechanisms through which nighttime light pollution may impact Alzheimer’s disease.

One of them is the role of sleep disruption. Wilson says the impact this can have on the brain’s processes is an important factor to consider.

“We know that sleep plays an important role in clearing the protein associated with Alzheimer’s disease, known as amyloid-beta, from the brain. If sleep is disrupted, by things such as light or an untreated sleep disorder such as sleep apnoea, the ability for our brain to clear this protein is reduced. Further, poor sleep quality may have a broader impact on other risk factors, such as depression, level of physical activity, and high blood pressure,” she said.

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