Adamantane antivirals are only active against influenza A virus, an RNA virus, but has no action against influenza B virus. A viral membrane protein, M2, functions as an ion channel at two stages of the viral replication within the host cell. These stages are the fusion of viral membrane and endosome membrane, and the assembly and release of new virions. Adamantane antivirals block this ion channel.
Name | Updated |
---|---|
Rimantadine (Rimantadine [ ri-man-ta-deen ]) | 12-Aug-2023 |
Flumadine (Rimantadine [ ri-man-ta-deen ]) | 13-Jul-2023 |
Amantadine (Amantadine) | 10-Jul-2023 |