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Amylin analogs are used in the treatment of diabetes. They are stable synthetic compounds, which are administered subcutaneously before meals, and work similarly to the physiological amylin.

Amylin is a 37 amino acid polypeptide hormone that is secreted with insulin from the beta cells in the pancreas. In diabetes, as less insulin is secreted there is also a deficiency of amylin. Amylin assists insulin in postprandial glucose control. It inhibits glucagon secretion, delays gastric emptying and signals satiety, suppressing the intake of food.