Miscellaneous antihyperlipidemic agents are used to treat hyperlipidemia. They help to decrease total cholesterol by lowering low-density lipoprotein (LDL) cholesterol and triglycerides and raising high-density lipoproteins (HDL) cholesterol. Niacin (nicotinic acid) is a water-soluble B vitamin, which inhibits the synthesis of cholesterol and triglycerides, therefore lowers total cholesterol and triglyceride levels, and raises HDL cholesterol levels.