Other cephalosporins include new cephalosporins that do not fit into one of the five existing generations of cephalosporins.
Cefiderocol is a first in its class siderophore cephalosporin with a unique mechanism of action and structure that combines a catechol-type siderophore (these chelate ferric iron via hydroxyl groups) with a cephalosporin core. This gives it enhanced stability against hydrolysis by many β-lactamases, including extended-spectrum β-lactamases, such as CTX-M, and carbapenemases.
Name | Updated |
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Cefiderocol (Cefiderocol [ sef-i-der-oh-kol ]) | 15-Aug-2023 |
Fetroja (Cefiderocol [ sef-i-der-oh-kol ]) | 13-Jul-2023 |