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Immunosuppressive agents are drugs that suppress the immune system and reduce the risk of rejection of foreign bodies such as transplant organs. Different classes of immunosuppressive agents have different mechanism of action. Now immunosuppressive agents are used as cancer chemotherapy, in autoimmune diseases such as rheumatoid arthritis and to treat severe allergy. As immunosuppressive agents lower the immunity there is increased risk of infection. Immunosuppressants can be divided into classes including calcineurin inhibitors, interleukin inhibitors, selective immunosuppressants and TNF alfa inhibitors. Immunosuppressants that do not fit into these classes are categorized as other immunosuppressants.