Thioxanthenes are typical (conventional) antipsychotic drugs structurally related to phenothiazines. They work as dopamine-2 (D2) receptor antagonists and suppress the effect of dopamine in the brain.
Thioxanthenes are high potency drugs: they have a high affinity for dopamine receptors compared to affinity for adrenergic and muscarinic receptors. Thioxanthene antipsychotics are used to treat schizophrenia.
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Thiothixene (Thiothixene [ thye-oh-thix-een ]) | 12-Aug-2023 |