Carbamazepine (Oral)

Drug Detail:Carbamazepine (Carbamazepine (oral) [ kar-ba-maz-e-peen ])

Generic Name: carbamazepine [ kar-ba-MAZ-e-peen ]

Drug Class: Dibenzazepine anticonvulsants

Oral route(Tablet;Tablet, Chewable;Suspension;Tablet, Extended Release;Capsule, Extended Release)

Serious and sometimes fatal dermatologic reactions (including Stevens-Johnson syndrome and toxic epidermal necrolysis) have been reported, especially in patients with the inherited allelic variant HLA-B*1502. Screen genetically at-risk patients prior to receiving carbamazepine. Do not start carbamazepine in patients who test positive for the allele unless the benefit clearly outweighs the risk. Discontinue if you suspect that the patient has a serious dermatologic reaction. Aplastic anemia and agranulocytosis have also been reported. Obtain pretreatment hematological testing and periodically monitor CBC. Consider drug discontinuation if significant bone marrow depression develops .

Uses for carbamazepine

Carbamazepine is used to treat certain types of seizures (eg, partial seizures, tonic-clonic seizures) and bipolar disorder. It is also used to relieve pain caused by trigeminal neuralgia (tic douloureux).

This medicine is available only with your doctor's prescription.

Before using carbamazepine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Equetro® extended-release capsules in children with partial seizures, generalized tonic-clonic seizures, and mixed seizure patterns. Safety and efficacy have been established.

Appropriate studies have not been performed on the relationship of age to the effects of Equetro® extended-release capsules in children with bipolar disorder and pain of trigeminal neuralgia. Safety and efficacy have not been established.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Tegretol® chewable tablets, suspension, tablets, or extended-release capsules in children with partial seizures, generalized tonic-clonic seizures, mixed seizure patterns, bipolar disorder, and pain of trigeminal neuralgia.

Geriatric

Although appropriate studies on the relationship of age to the effects of carbamazepine have not been performed in the geriatric population, geriatric-specific problems are not expected to limit the usefulness of carbamazepine in the elderly. However, elderly patients are more likely to have confusion, hyponatremia (low sodium in the blood), or agitation and age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving carbamazepine.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Artemether
Atazanavir
Boceprevir
Cabotegravir
Clorgyline
Cobicistat
Daclatasvir
Darunavir
Dasabuvir
Delamanid
Delavirdine
Doravirine
Efavirenz
Elbasvir
Elvitegravir
Fostemsavir
Furazolidone
Grazoprevir
Iproniazid
Isavuconazonium
Isocarboxazid
Lenacapavir
Linezolid
Lorlatinib
Lumefantrine
Lurasidone
Maraviroc
Mavacamten
Methylene Blue
Moclobemide
Nefazodone
Nialamide
Nirmatrelvir
Ombitasvir
Pacritinib
Pargyline
Paritaprevir
Phenelzine
Praziquantel
Procarbazine
Ranolazine
Rasagiline
Rilpivirine
Ritonavir
Selegiline
Telaprevir
Tenofovir Alafenamide
Toloxatone
Tranylcypromine
Voriconazole

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Abemaciclib
Abiraterone Acetate
Acalabrutinib
Acetazolamide
Adagrasib
Adenosine
Afatinib
Alfentanil
Almotriptan
Alpelisib
Alprazolam
Amiodarone
Amodiaquine
Amphetamine
Amprenavir
Apixaban
Apremilast
Aprepitant
Aripiprazole
Artesunate
Atogepant
Avacopan
Avapritinib
Axitinib
Bedaquiline
Belumosudil
Bendamustine
Benzhydrocodone
Benzphetamine
Berotralstat
Betrixaban
Bictegravir
Bortezomib
Bosutinib
Brexpiprazole
Brigatinib
Buprenorphine
Bupropion
Butorphanol
Cabozantinib
Calcifediol
Cannabidiol
Capmatinib
Cariprazine
Cenobamate
Ceritinib
Chloroquine
Chlorpromazine
Cisatracurium
Citalopram
Clarithromycin
Clonazepam
Clozapine
Cobimetinib
Codeine
Conivaptan
Copanlisib
Crizotinib
Cyclophosphamide
Cyclosporine
Dabigatran Etexilate
Daridorexant
Darolutamide
Dasatinib
Deflazacort
Desmopressin
Desogestrel
Desvenlafaxine
Dexamethasone
Dextroamphetamine
Dextromethorphan
Dienogest
Dihydrocodeine
Diltiazem
Dolasetron
Dolutegravir
Doxorubicin
Doxorubicin Hydrochloride Liposome
Dronedarone
Drospirenone
Duloxetine
Duvelisib
Edoxaban
Elacestrant
Elexacaftor
Eliglustat
Encorafenib
Entrectinib
Enzalutamide
Eravacycline
Erdafitinib
Erlotinib
Erythromycin
Escitalopram
Eslicarbazepine Acetate
Estetrol
Estradiol
Ethinyl Estradiol
Ethynodiol
Etonogestrel
Etravirine
Everolimus
Exemestane
Ezogabine
Fedratinib
Felodipine
Fenfluramine
Fentanyl
Fexinidazole
Finerenone
Fluconazole
Fluoxetine
Fosamprenavir
Fosaprepitant
Fosnetupitant
Fosphenytoin
Fostamatinib
Futibatinib
Gefitinib
Gestodene
Gilteritinib
Glasdegib
Glecaprevir
Granisetron
Halofantrine
Hemin
Hydrocodone
Hydromorphone
Hydroxyamphetamine
Hydroxychloroquine
Hydroxytryptophan
Ibrexafungerp
Ibrutinib
Idelalisib
Ifosfamide
Imatinib
Indinavir
Infigratinib
Irinotecan
Irinotecan Liposome
Isoniazid
Istradefylline
Itraconazole
Ivabradine
Ivacaftor
Ivosidenib
Ixabepilone
Ixazomib
Ketoconazole
Lamotrigine
Lapatinib
Larotrectinib
Lasmiditan
Ledipasvir
Lefamulin
Lemborexant
Leniolisib
Levoketoconazole
Levomilnacipran
Levonorgestrel
Levorphanol
Linagliptin
Lisdexamfetamine
Lomitapide
Lopinavir
Loratadine
Lorcaserin
Loxapine
Lumateperone
Lurbinectedin
Macimorelin
Macitentan
Manidipine
Maribavir
Medroxyprogesterone
Mefloquine
Meperidine
Mestranol
Metaxalone
Methadone
Methamphetamine
Methotrexate
Midostaurin
Mifepristone
Mirtazapine
Mitapivat
Mobocertinib
Morphine
Morphine Sulfate Liposome
Nalbuphine
Naloxegol
Nelfinavir
Neratinib
Netupitant
Nifedipine
Nilotinib
Nimodipine
Nintedanib
Nomegestrol
Norelgestromin
Norethindrone
Norgestimate
Norgestrel
Olanzapine
Olaparib
Olutasidenib
Omaveloxolone
Ondansetron
Orlistat
Osimertinib
Oxcarbazepine
Oxycodone
Oxymorphone
Paclitaxel
Palbociclib
Paliperidone
Palonosetron
Panobinostat
Pazopanib
Pemigatinib
Pentazocine
Perampanel
Pexidartinib
Phenobarbital
Phenytoin
Pibrentasvir
Piperaquine
Pirtobrutinib
Pitolisant
Ponatinib
Ponesimod
Pralsetinib
Pretomanid
Primaquine
Primidone
Proguanil
Propoxyphene
Pyrimethamine
Quetiapine
Quinine
Regorafenib
Relugolix
Remifentanil
Ribociclib
Rimegepant
Ripretinib
Risperidone
Rivaroxaban
Rolapitant
Romidepsin
Ruxolitinib
Samidorphan
Saquinavir
Segesterone
Selpercatinib
Selumetinib
Sertraline
Sildenafil
Simvastatin
Sirolimus Protein-Bound
Sofosbuvir
Sonidegib
Sotorasib
Sparsentan
Stiripentol
Sufentanil
Sunitinib
Tacrolimus
Tafenoquine
Tamoxifen
Tapentadol
Tasimelteon
Tazemetostat
Telithromycin
Temsirolimus
Terfenadine
Tezacaftor
Thioridazine
Thiotepa
Ticagrelor
Tipranavir
Tivozanib
Tofacitinib
Tolvaptan
Topiramate
Trabectedin
Tramadol
Trazodone
Tucatinib
Ubrogepant
Ulipristal
Upadacitinib
Valbenazine
Valproic Acid
Vandetanib
Velpatasvir
Vemurafenib
Venetoclax
Verapamil
Vigabatrin
Vilazodone
Vincristine
Vincristine Sulfate Liposome
Vinflunine
Voclosporin
Vonoprazan
Vorapaxar
Vortioxetine
Voxelotor
Voxilaprevir
Zanubrutinib
Zileuton
Ziprasidone
Zolpidem

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acetaminophen
Acetylcysteine
Aminophylline
Amitriptyline
Amoxapine
Anisindione
Aripiprazole Lauroxil
Caspofungin
Dalfopristin
Danazol
Desipramine
Dicumarol
Doxepin
Etretinate
Felbamate
Flunarizine
Furosemide
Ginkgo
Haloperidol
Hydrochlorothiazide
Imipramine
Influenza Virus Vaccine
Levetiracetam
Lithium
Methylphenidate
Methylprednisolone
Metronidazole
Mianserin
Midazolam
Miokamycin
Nafimidone
Niacinamide
Nortriptyline
Omeprazole
Ospemifene
Phenprocoumon
Pipecuronium
Protriptyline
Psyllium
Quinupristin
Remacemide
Rifampin
Rifapentine
Rocuronium
Rufinamide
Sabeluzole
Semaglutide
Theophylline
Tiagabine
Ticlopidine
Troleandomycin
Valnoctamide
Vecuronium
Viloxazine
Warfarin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

Grapefruit Juice

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

Black Tea

Proper use of carbamazepine

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

This medicine comes with a Medication Guide Read and follow the instructions carefully. Ask your doctor if you have any questions.

Tegretol® should be taken with meals to lessen unwanted effects (eg, stomach upset, nausea, vomiting). You may take Equetro® with or without food.

You may swallow the extended-release capsules whole, or open it and sprinkle the contents over a teaspoon of applesauce. Swallow the mixture right away. Do not crush or chew the beads.

Swallow the extended-release tablets whole. Do not crush or chew it. Do not take the extended-release tablets that are damaged or have chips or cracks.

Grapefruit and grapefruit juice may increase the effects of this medicine by increasing the amount in the body. Do not eat grapefruit or drink grapefruit juice while you are taking this medicine.

If you are taking this medicine for pain relief:

Carbamazepine is not an ordinary pain reliever. It should be used only when a doctor prescribes it for certain kinds of pain. Do not take carbamazepine for any other aches or pains.

If you are taking Tegretol® oral liquid:

Shake the oral liquid well before each use. Measure your dose with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.
Do not take any other liquid medicines at the same time that you take your dose of Tegretol® without first checking with your doctor.

Tegretol® tablets work differently than the Tegretol® oral liquid, even at the same dose (number of milligrams). Do not switch from the tablets to the oral liquid unless your doctor tells you to.

Tegretol® may be used alone or together with other seizure medicines. Ask your doctor first before taking any other seizure medicine together with Tegretol®.

Do not take Equetro® capsules if you are also using Tegretol® suspension or tablets. These medicines should not be taken together because both medicines contains carbamazepine. Ask your doctor if you have any questions.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (extended-release capsules):
- For bipolar disorder:
  - Adults—At first, 200 milligrams (mg) 2 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 1600 mg per day.
  - Children—Use and dose must be determined by your doctor.
- For epilepsy:
  - Adults and children 12 years of age and older—At first, 200 milligrams (mg) 2 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 500 to 800 mg 2 times a day.
  - Children younger than 12 years of age—Dose is based on body weight and must be determined by your doctor. However, the dose is usually not more than 1000 mg per day.
- For trigeminal neuralgia:
  - Adults—At first, 200 milligrams (mg) once a day. Your doctor may increase your dose as needed and tolerated. However, the dose is usually not more than 1200 mg per day.
  - Children—Use and dose must be determined by your doctor.
For oral dosage form (extended-release tablets):
- For epilepsy:
  - Adults—At first, 200 mg 2 times a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 1000 to 1600 mg per day.
  - Children 6 to 12 years of age—At first, 100 mg 2 times a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 1000 mg per day.
  - Children younger than 6 years of age—Dose is based on body weight and will be determined by your doctor. The dose is usually 10 to 20 milligram (mg) per kilogram (kg) per day, taken 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 35 mg per kg of body weight per day.
- For trigeminal neuralgia:
  - Adults—At first, 100 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 1200 mg per day.
  - Children—Use and dose must be determined by your doctor.
For oral dosage form (oral liquid):
- For epilepsy:
  - Adults—100 milligrams (mg) or 1 teaspoon 4 times a day (400 mg per day). Your doctor may adjust your dose as needed. However, the dose is usually not more than 1000 to 1600 mg per day.
  - Children 6 to 12 years of age—At first, 50 milligrams (mg) or one-half teaspoon 4 times a day (200 mg per day). Your doctor may adjust your dose as needed. However, the dose is usually not more than 1000 mg per day.
  - Children younger than 6 years of age—Dose is based on body weight and will be determined by your doctor. The dose is 10 to 20 milligrams (mg) per kilogram (kg) of body weight per day, taken 4 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 35 mg per kg of body weight per day.
- For trigeminal neuralgia:
  - Adults—At first, 50 milligrams (mg) or one-half teaspoon 4 times a day (200 mg per day). Your doctor may adjust your dose as needed. However, the dose is usually not more than 1200 mg per day.
  - Children—Use and dose must be determined by your doctor.
For oral dosage forms (tablets or chewable tablets):
- For epilepsy:
  - Adults—At first, 200 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 1000 to 1600 mg per day.
  - Children 6 to 12 years of age—At first, 100 mg 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 1000 mg per day.
  - Children younger than 6 years of age—Dose is based on body weight and will be determined by your doctor. The dose is 10 to 20 milligrams (mg) per kilogram (kg) of body weight per day, taken 3 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 35 mg per kg of body weight per day.
- For trigeminal neuralgia:
  - Adults and teenagers—At first, 100 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 1200 mg per day.
  - Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions while using carbamazepine

It is very important that your doctor check your or your child's progress at regular visits to make sure this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects.

Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.

Do not take carbamazepine together with a monoamine oxidase inhibitor (MAOI) or during the first 14 days after you stop taking a MAOI. MAOIs are used for depression and some examples are isocarboxazid (Marplan®), phenelzine (Nardil®), procarbazine (Matulane®), selegiline (Eldepryl®), or tranylcypromine (Parnate®). Do not use this medicine together with nefazodone (Serzone®) and certain medicines for HIV/AIDS (such as delavirdine, efavirenz, Atripla®, Sustiva®, Rescriptor®).

If you plan to have children, talk with your doctor before using this medicine. Some men using this medicine have become infertile (unable to have children).

Carbamazepine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you, your child, or your caregiver notice any of these unwanted effects, tell your doctor right away.

Check with your doctor right away if a fever, sore throat, rash, ulcers in the mouth, nosebleeds, bleeding gums, swollen glands, or small red or purple spots on the skin occur. These could be symptoms of a serious blood problem.

This medicine may cause serious skin reactions (eg, Stevens-Johnson syndrome and toxic epidermal necrolysis), which can be life-threatening and require immediate medical attention. Check with your doctor right away if you or your child has blistering, peeling, or loosening of the skin, chills, cough, diarrhea, itching, joint or muscle pain, red irritated eyes, red skin lesions, often with a purple center, sore throat, sores, ulcers, or white spots in the mouth, or on the lips, or unusual tiredness or weakness while you are using this medicine.

This medicine may cause a condition called drug reaction with eosinophilia and systemic symptoms (DRESS), which is a serious allergic reaction affecting multiple body organs (eg, liver or kidney). Check with your doctor right away if you have fever, dark urine, headache, rash, stomach pain, swollen, painful, or tender lymph glands in the neck, armpit, or groin, unusual tiredness, or yellow eyes or skin.

This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you, your child, or your caregiver notice any of these side effects, tell your doctor or your child's doctor right away.

This medicine may cause serious allergic reactions, including anaphylaxis and angioedema, which can be life-threatening and require immediate medical attention. Tell your doctor right away if you or your child have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after using this medicine.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that cause drowsiness). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds, sedatives, tranquilizers, or sleeping medicine, prescription pain medicine or narcotics, medicine for seizures (eg, barbiturates), muscle relaxants, or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you or your child are using this medicine.

This medicine may cause some people to become drowsy, dizzy, lightheaded, or less alert than they are normally, especially when they are starting treatment or increasing the dose. It may also cause blurred or double vision, weakness, or loss of muscle control in some people. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

Check with your doctor immediately if blurred vision, difficulty in reading, or any other changes in vision occur during or after treatment. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).

Some people who take carbamazepine may become more sensitive to sunlight than they are normally. Exposure to sunlight, even for brief periods of time, may cause skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. When you begin taking this medicine:

Stay out of direct sunlight, especially between the hours of 10:00 AM and 3:00 PM, if possible.
Wear protective clothing, including a hat. Also, wear sunglasses.
Apply a sun block product that has a sun protection factor (SPF) of at least 15. Some patients may require a product with a higher SPF number, especially if they have a fair complexion. If you have any questions about this, check with your doctor.
Apply a sun block lipstick that has an SPF of at least 15 to protect your lips.
Do not use a sunlamp or tanning bed or booth.

If you have a severe reaction from the sun, check with your doctor.

Before having any medical tests, tell the medical doctor in charge that you are taking this medicine. The results of some pregnancy tests may be affected by this medicine.

Do not stop taking this medicine without first checking with your doctor. Your doctor may want you or your child to gradually reduce the amount you are using before stopping it completely. This may help prevent worsening of seizures and reduce the possibility of withdrawal symptoms.

Birth control pills containing estrogen may not work properly if you take them while you are taking carbamazepine. Unplanned pregnancies may occur. Use a different or additional means of birth control while you are taking carbamazepine. If you have any questions about this, check with your doctor.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Side Effects of carbamazepine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Blurred vision or double vision
continuous back-and-forth eye movements

Less common

Actions that are out of control
behavioral changes (especially in children)
confusion, agitation, or hostility (especially in the elderly)
diarrhea (severe)
discouragement
drooling
fear
feeling of unreality
feeling sad or empty
headache (continuing)
increase in seizures
irritability
lack of appetite
loss of balance control
loss of interest or pleasure
muscle trembling, jerking, or stiffness
nausea (severe)
other problems with muscle control or coordination
sense of detachment from self or body
shakiness and unsteady walk
shuffling walk
stiffness of the arm or leg
sudden, wide mood swings
talking, feeling, and acting with excitement
thoughts or attempts of killing oneself
tiredness
trouble concentrating
trouble sleeping
twisting movements of the body
uncontrolled movements, especially of the face, neck, and back
unusual drowsiness
vomiting (severe)

Rare

Black, tarry stools
blood in the urine or stools
bone or joint pain
chest pain or tightness
cough
darkening of the urine
difficulty with speaking or slurred speech
fainting
frequent urination
hoarseness
irregular, pounding, or unusually slow heartbeat
lower back or side pain
mental depression with restlessness and nervousness or other mood or mental changes
muscle or stomach cramps
nosebleeds or other unusual bleeding or bruising
numbness, tingling, pain, or weakness in the hands and feet
pain, tenderness, swelling, or bluish color in the leg or foot
painful or difficult urination
pale stools
pinpoint red spots on the skin
rapid weight gain
rigidity
ringing, buzzing, or other unexplained sounds in the ears
skin rash, hives, or itching
sores, ulcers, or white spots on the lips or in the mouth
swelling of the face, hands, feet, or lower legs
swollen or painful glands
sudden decrease in the amount of urine
trembling
trouble breathing
uncontrolled body movements
unusual tiredness or weakness
visual hallucinations (seeing things that are not there)
yellow eyes or skin

Incidence not known

Blistering, peeling, or loosening of the skin
chills
decreased urine output
dilated neck veins
extreme tiredness or weakness
general feeling of discomfort or illness
irregular breathing
irregular heartbeat
joint or muscle pain
red skin lesions, often with a purple center
red, irritated eyes
sore throat
swelling of the face, fingers, feet, or lower legs
thickening of bronchial secretions
unusual bleeding or bruising
weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Dizziness (mild)
drowsiness (mild)
lightheadedness
nausea (mild)
vomiting (mild)

Incidence not known

Accidental injury
aching joints or muscles
back pain
belching
constipation
dryness of the mouth
headache
heartburn
increased sensitivity of the skin to sunlight (skin rash, itching, redness or other discoloration of the skin, or severe sunburn)
increased sweating
indigestion
irritation or soreness of the tongue or mouth
lack or loss of strength
loss of hair
loss of memory
problems with memory
sexual problems in males
sleepiness
stomach pain, upset, or discomfort

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Name	Drug Class	Updated
Fidanacogene Elaparvovec	Drugs	03-Oct-2024
Cerave Anti-Itch	Drugs	02-Oct-2024
Centrum Adult	Drugs	02-Oct-2024
Crovalimab	Drugs	02-Oct-2024
Cyltezo Prefilled Syringe	Drugs	01-Oct-2024
Zepbound Pen	Drugs	30-Sep-2024
Mylanta One	Drugs	27-Sep-2024
Uretron Ds	Drugs	27-Sep-2024
Medihoney Wound And Burn Dressing	Drugs	26-Sep-2024
Lidotrode	Drugs	26-Sep-2024
Libervant	Drugs	26-Sep-2024
Moderna Covid-19	Drugs	25-Sep-2024
Beqvez	Drugs	24-Sep-2024
Beqvez	Drugs	24-Sep-2024
Beqvez	Drugs	24-Sep-2024

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