Applies to alclometasone topical: external cream, external ointment.

Serious side effects

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
• Signs of a weak adrenal gland like a very bad upset stomach or throwing up, very bad dizziness or passing out, muscle weakness, feeling very tired, mood changes, not hungry, or weight loss.
• Signs of Cushing's disease like weight gain in the upper back or belly, moon face, very bad headache, or slow healing.
• Change in color of skin.
• Skin changes (pimples, stretch marks, slow healing, hair growth).
• Irritation where this drug is used.

Other side effects

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if you have any side effects that bother you or do not go away.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

For Healthcare Professionals

Applies to alclometasone topical: topical cream, topical ointment.

General

The most commonly reported side effects were itching, burning, erythema, dryness, irritation, and papular rashes.^[Ref]

Endocrine

Frequency not reported: Cushings syndrome^[Ref]

Dermatologic

Common (1% to 10%): Papular rash

Frequency not reported: Folliculitis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, striae, miliaria, secondary infection, hypertrichosis, skin maceration, skin atrophy^[Ref]

Local

Common (1% to 10%): Itching, burning, erythema, dryness, irritation

Rare (less than 0.1%): Stinging^[Ref]

Metabolic

Frequency not reported: Hyperglycemia^[Ref]

Renal

Frequency not reported: Glucosuria^[Ref]