Applies to aluminum hydroxide / magnesium hydroxide / simethicone: oral liquid, oral suspension, oral tablet chewable.
Serious side effects
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
Other side effects
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Constipation.
- Diarrhea.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
For Healthcare Professionals
Applies to aluminum hydroxide/magnesium hydroxide/simethicone: oral suspension, oral tablet chewable.
Gastrointestinal
Uncommon (0.1% to 1%): Constipation, diarrhea
Frequency not reported: Abdominal pain[Ref]
Metabolic
Very rare (less than 0.01%): Hypermagnesemia
Frequency not reported: Hyperaluminemia, hyperphosphatemia[Ref]
Hypersensitivity
Frequency not reported: Anaphylactic reaction, angioedema, hypersensitivity reactions[Ref]
Dermatologic
Frequency not reported: Pruritus, urticaria[Ref]
Musculoskeletal
Frequency not reported: Increased bone resorption, osteomalacia[Ref]
Renal
Frequency not reported: Hypercalciuria[Ref]
