Applies to aminocaproic acid: oral solution, oral tablet. Other dosage forms:

• intravenous solution

Serious side effects of Aminocaproic acid

Along with its needed effects, aminocaproic acid may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking aminocaproic acid:

Incidence not known

• Anxiety
• black, tarry stools
• bleeding gums
• blood in the urine or stools
• blurred vision
• change in the ability to see colors, especially blue or yellow
• chest pain or discomfort
• chills
• confusion
• cough or hoarseness
• dark-colored urine
• decreased frequency or amount of urine
• difficult or labored breathing
• difficulty with moving
• difficulty with speaking
• difficulty with swallowing
• dizziness or lightheadedness
• dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
• double vision
• fainting
• fast heartbeat
• fever with or without chills
• general feeling of discomfort or illness
• general feeling of tiredness or weakness
• headache
• hives
• inability to move the arms, legs, or facial muscles
• inability to speak
• increased thirst
• itching of the skin
• joint pain
• loss of appetite
• lower back or side pain
• muscle aching or cramping
• muscle cramps or spasms
• muscle pain or stiffness
• muscular pain, tenderness, wasting, or weakness
• nausea and vomiting
• numbness and tingling of the face, fingers, or toes
• pain in the arms, legs, or lower back, especially pain in the calves or heels upon exertion
• painful or difficult urination
• pale, bluish-colored, or cold hands or feet
• pinpoint red spots on the skin
• problems with bleeding or clotting
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• shortness of breath
• skin rash
• slow or irregular heartbeat
• slow speech
• sore throat
• sores, ulcers, or white spots on the lips or in the mouth
• sudden shortness of breath or troubled breathing sweating
• swelling
• swelling of the face, fingers, or lower legs
• swollen glands
• swollen joints
• tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area
• tightness in the chest
• troubled breathing
• unusual bleeding or bruising
• unusual tiredness or weakness
• vomiting
• weak or absent pulses in the legs
• weight gain
• wheezing

Other side effects of Aminocaproic acid

Some side effects of aminocaproic acid may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

• Abdominal or stomach pain
• confusion as to time, place, or person
• continuing ringing or buzzing or other unexplained noise in the ears
• decreased vision
• diarrhea
• ejaculation without semen
• hearing loss
• holding false beliefs that cannot be changed by fact
• mood or mental changes
• seeing, hearing, or feeling things that are not there
• stuffy nose
• unusual excitement, nervousness, or restlessness
• watery eyes

For Healthcare Professionals

Applies to aminocaproic acid: compounding powder, intravenous solution, oral liquid, oral tablet.

Nervous system

Frequency not reported: Headache, convulsions, dizziness, intracranial hypertension, stroke, syncope, tinnitus^[Ref]

Musculoskeletal

Frequency not reported: Creatine phosphokinase increased, muscle weakness, myalgia, myopathy, myositis, rhabdomyolysis^[Ref]

Cardiovascular

Frequency not reported: Bradycardia, hypotension, peripheral ischemia, thrombosis^[Ref]

Gastrointestinal

Frequency not reported: Abdominal pain, diarrhea, nausea, vomiting^[Ref]

Hematologic

Frequency not reported: Agranulocytosis, coagulation disorder, leukopenia, thrombocytopenia^[Ref]

Local

Frequency not reported: Injection site reactions, injection site pain, injection site necrosis^[Ref]

Psychiatric

Frequency not reported: Confusion, delirium, hallucinations^[Ref]

Respiratory

Frequency not reported: Dyspnea, nasal congestion, pulmonary embolism^[Ref]

Dermatologic

Frequency not reported: Pruritus, rash^[Ref]

Immunologic

Frequency not reported: Allergic and anaphylactic reactions, anaphylaxis^[Ref]

Ocular

Frequency not reported: Vision decreased, watery eyes^[Ref]

Renal

Frequency not reported: BUN increased, renal failure^[Ref]

Genitourinary

Frequency not reported: Dry ejaculation^[Ref]

Metabolic

Frequency not reported: Edema^[Ref]

Other

Frequency not reported: Malaise^[Ref]