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Home > Drugs > Anacaulase (monograph) > Anacaulase (monograph) Side Effects
Drugs

Anacaulase topical Side Effects

Applies to anacaulase topical: topical application gel/jelly.

Serious side effects of Anacaulase topical

Along with its needed effects, anacaulase topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking anacaulase topical:

More common

  • Pale skin
  • trouble breathing
  • unusual bleeding or bruising
  • unusual tiredness or weakness

Less common

  • Bladder pain
  • bloody or cloudy urine
  • blurred vision
  • confusion
  • cough or hoarseness
  • difficult, burning, or painful urination
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • eye pain
  • fast, pounding, or irregular heartbeat or pulse
  • fever or chills
  • frequent urge to urinate
  • general feeling of illness
  • headache
  • lower back or side pain
  • sore throat
  • stomach pain
  • sweating

Incidence not known

  • Chest tightness
  • difficulty swallowing
  • hives, itching, skin rash
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

Other side effects of Anacaulase topical

Some side effects of anacaulase topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Trouble sleeping
  • vomiting

Less common

  • Scar

For Healthcare Professionals

Applies to anacaulase topical: topical gel.

Cardiovascular

Common (1% to 10%): Tachycardia[Ref]

Dermatologic

Very common (10% or more): Pruritus (15%)

Common (1% to 10%): Decubitus ulcer, rash, scar[Ref]

Gastrointestinal

Common (1% to 10%): Vomiting[Ref]

General

The most common adverse reactions with a frequency of greater than 10% were pruritus and pyrexia.

Genitourinary

Common (1% to 10%): Urinary tract infection[Ref]

Hematologic

Common (1% to 10%): Anemia, hypotension, leukocytosis, subcutaneous hematoma[Ref]

Hepatic

Common (1% to 10%): Abnormal hepatic function[Ref]

Hypersensitivity

Common (1% to 10%): Drug hypersensitivity

Postmarketing reports: Hypersensitivity (including anaphylaxis and urticaria)[Ref]

Local

Wound complication includes skin graft failure, graft loss, graft complication, and wound decomposition.[Ref]

Common (1% to 10%): Wound complication[Ref]

Nervous system

Very common (10% or more): Pyrexia (12%)

Common (1% to 10%): Insomnia[Ref]

Other

Common (1% to 10%): Bacteremia, infection, sepsis[Ref]

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