Summary of Use during Lactation

No information is available on the excretion of voclosporin into breastmilk. Because voclosporin has a molecular weight of 1214 Da and is 97%, plasma protein bound, it is unlikely to enter breastmilk in large amounts. One infant was successfully breastfed with careful timing of doses and breastfeeding. However, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. The manufacturer recommends that breastfeeding be avoided during voclosporin use and for at least 7 days after the last dose.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Azathioprine, Cyclosporine,

Tacrolimus,

Prednisone

Substance Name

Voclosporin

CAS Registry Number

515814-01-4

Drug Class

Breast Feeding

Lactation

Immunosuppressive Agents