Summary

Commonly reported side effects of buspirone include: dizziness. Other side effects include: headache and nervousness. Continue reading for a comprehensive list of adverse effects.

Applies to buspirone: oral tablets.

Side effects include:

Dizziness, nausea, headache, nervousness, drowsiness, light-headedness, excitement.

For Healthcare Professionals

Applies to buspirone: compounding powder, oral tablet.

Nervous system

Very common (10% or more): Dizziness (12%), drowsiness (10%)

Common (1% to 10%): Lightheadedness, decreased concentration, numbness, paresthesia, incoordination, headache, tremor, syncope, seizures

Rare (less than 0.1%): Cerebrovascular accident

Very rare (less than 0.01%): Serotonin syndrome, amnesia, cogwheel rigidity, dystonia/dystonic reactions, dyskinesias (acute and tardive), ataxias, parkinsonism, akathisia, restless leg syndrome

Postmarketing reports: Vertigo, extrapyramidal symptoms, transient difficulty with recall^[Ref]

Cardiovascular

Common (1% to 10%): Tachycardia/palpitations, chest pain

Uncommon (0.1% to 1%): Hypotension, hypertension

Rare (less than 0.1%): Congestive heart failure, myocardial infarction, cardiomyopathy, bradycardia^[Ref]

Dermatologic

Common (1% to 10%): Rash, sweating/clamminess

Uncommon (0.1% to 1%): Pruritus, flushing, easy bruising, hair loss, dry skin, facial edema, blisters

Rare (less than 0.1%): Acne, thinning of nails, ecchymosis, urticaria^[Ref]

Gastrointestinal

Common (1% to 10%): Nausea, dry mouth, abdominal/gastric distress, diarrhea, constipation, vomiting

Uncommon (0.1% to 1%): Flatulence, anorexia, increased appetite, salivation, irritable colon, rectal bleeding

Rare (less than 0.1%): Burning of the tongue^[Ref]

Musculoskeletal

Common (1% to 10%): Musculoskeletal aches/pains

Uncommon (0.1% to 1%): Muscle cramps, muscle spasms, rigid/stiff muscles, arthralgias

Rare (less than 0.1%): Muscle weakness^[Ref]

Ocular

Common (1% to 10%): Blurred vision

Uncommon (0.1% to 1%): Eye redness and itching, conjunctivitis, eye pain, eye pressure, photophobia

Very rare (less than 0.01%): Visual changes (including tunnel vision)^[Ref]

Other

Common (1% to 10%): Fatigue, weakness, tinnitus, sore throat

Uncommon (0.1% to 1%): Altered taste, altered smell, inner ear abnormality, edema, fever, roaring sensation in the head, malaise

Rare (less than 0.1%): Alcohol abuse, loss of voice, hiccoughs^[Ref]

Psychiatric

Common (1% to 10%): Insomnia, nervousness, excitement, anger/hostility, confusion, depression, dream disturbances, attention disturbance, sleep disorder

Uncommon (0.1% to 1%): Depersonalization, dysphoria, noise intolerance, euphoria, akathisia, fearfulness, loss of interest, dissociative reaction, hallucinations, involuntary movements, slowed reaction time, suicidal ideation, decreased or increased libido

Rare (less than 0.1%): Claustrophobia, cold intolerance, stupor, slurred speech, psychosis, delayed ejaculation, impotence

Very rare (less than 0.01%): Depersonalization

Postmarketing reports: Emotional lability, restlessness^[Ref]

Respiratory

Common (1% to 10%): Nasal congestion, pharyngolaryngeal pain

Uncommon (0.1% to 1%): Hyperventilation, shortness of breath, chest congestion

Rare (less than 0.1%): Epistaxis^[Ref]

Genitourinary

Uncommon (0.1% to 1%): Urinary frequency, urinary hesitancy, menstrual irregularity and spotting, dysuria

Rare (less than 0.1%): Amenorrhea, pelvic inflammatory disease, enuresis, nocturia

Very rare (less than 0.01%): Urinary retention^[Ref]

Hepatic

Uncommon (0.1% to 1%): Increases in hepatic aminotransferases (SGOT, SGPT)^[Ref]

Metabolic

Uncommon (0.1% to 1%): Weight gain, weight loss^[Ref]

Endocrine

Rare (less than 0.1%): Galactorrhea, thyroid abnormality^[Ref]

Hematologic

Rare (less than 0.1%): Eisonophilia, leukopenia, thrombocytopenia, bleeding disturbance^[Ref]

Hypersensitivity

Postmarketing reports: Allergic reactions, angioedema^[Ref]