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Home > Drugs > Covid-19 vaccine (pfizer-biontech) (monograph) > Covid-19 vaccine (pfizer-biontech) (monograph) Side Effects
Drugs

Sars-cov-2 mrna (tozinameran) vaccine Side Effects

Applies to sars-cov-2 mrna (tozinameran) vaccine: intramuscular suspension.

Local

Very common (10% or more): Pain at injection site (78.3% to 90.5%), injection site swelling (up to 10.5%)

Common (1% to 10%): Swelling, injection site redness/redness[Ref]

Nervous system

Bell's palsy occurred in 4 patients in the treatment group versus 2 patients in the placebo group. Onset of facial paralysis occurred on day 37 after dose 1 (patient only received one dose), and days 3, 9, and 48 after dose 2 in the treatment group; onset of facial paralysis was day 30 and 102 in the placebo group. Currently available information is insufficient to determine a causal relationship with the vaccine.[Ref]

Very common (10% or more): Headache (43.5% to 75.5%)

Uncommon (0.1% to 1%): Lethargy

Rare (0.01% to 0.1%): Bell's palsy

Postmarketing reports: Dizziness, syncope[Ref]

Other

Very common (10% or more): Fatigue (49.4 to 77.5%), use of antipyretic or pain medication (27.8% to 45.2%), fever of 38C or higher (4.1% to 24.3%)

Uncommon (0.1% to 1%): Malaise, asthenia[Ref]

Musculoskeletal

Very common (10% or more): Chills (16.5% to 49.2%), new or worsened muscle pain (22.9% to 42.2%), new or worsened joint pain (11.8% to 24.3%)

Postmarketing reports: Pain in extremity (arm)[Ref]

Gastrointestinal

Very common (10% or more): Diarrhea (up to 11.7%)

Common (1% to 10%): Nausea, vomiting

Uncommon (0.1% to 1%): Decreased appetite[Ref]

Hypersensitivity

Postmarketing reports: Severe allergic reactions including anaphylaxis, other hypersensitivity reactions (e.g., rash, pruritus, urticaria, angioedema)[Ref]

Cardiovascular

Postmarketing reports: Pericarditis, myocarditis[Ref]

Dermatologic

Uncommon (0.1% to 1%): Hyperhidrosis, night sweats[Ref]

Hematologic

Uncommon (0.1% to 1%): Lymphadenopathy[Ref]

Metabolic

Uncommon (0.1% to 1%): Decreased appetite[Ref]

Frequently asked questions

  • Can you take Ibuprofen after the COVID booster vaccine?
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