Note: This document contains side effect information about cytomegalovirus immune globulin. Some dosage forms listed on this page may not apply to the brand name CytoGam.
Applies to cytomegalovirus immune globulin: parenteral injection for iv infusion.
Side effects include:
Flushing, chills, muscle cramps, back pain, fever, nausea, vomiting, arthralgia, wheezing/shortness of breath/chest tightness.
For Healthcare Professionals
Applies to cytomegalovirus immune globulin: intravenous solution.
General
The most common adverse events were flushing, chills, muscle cramps, back pain, fever, nausea, vomiting, arthralgia, and wheezing. Such reactions are most often related to infusion rates.[Ref]
Renal
Frequency not reported: Increases in serum creatinine, increase in blood urea nitrogen (BUN), acute renal failure, acute tubular necrosis, proximal tubular nephropathy, osmotic nephrosis[Ref]
Cardiovascular
Uncommon (0.1% to 1%): Decrease in blood pressure
Frequency not reported: Flushing
Postmarketing reports: Cardiac arrest, thromboembolism, vascular collapse, hypotension[Ref]
Dermatologic
Postmarketing reports: Stevens-Johnson syndrome, epidermolysis, erythema multiforme, bullous dermatitis[Ref]
Gastrointestinal
Frequency not reported: Nausea, vomiting
Postmarketing reports: Abdominal pain[Ref]
Hematologic
Postmarketing reports: Pancytopenia, leukopenia, hemolysis, positive direct antiglobulin (Coombs) test[Ref]
Hepatic
Postmarketing reports: Hepatic dysfunction[Ref]
Musculoskeletal
Frequency not reported: Chills, muscle cramps, back pain, arthralgia[Ref]
Nervous system
Postmarketing reports: Coma, loss of consciousness, seizures, tremor[Ref]
Respiratory
Frequency not reported: Wheezing
Postmarketing reports: Apnea, acute respiratory distress syndrome (ARDS), transfusion related acute lung injury (TRALI), cyanosis, hypoxemia, pulmonary edema, dyspnea, bronchospasm[Ref]
Other
Postmarketing reports: Fever, rigors[Ref]
Genitourinary
Frequency not reported: Oliguria, anuria requiring dialysis
