Note: This document contains side effect information about atropine / hyoscyamine / phenobarbital / scopolamine. Some dosage forms listed on this page may not apply to the brand name Donnatal.

Summary

More frequent side effects include: constipation and dizziness. Continue reading for a comprehensive list of adverse effects.

Applies to atropine / hyoscyamine / phenobarbital / scopolamine: oral elixir, oral tablet.

Serious side effects of Donnatal

Along with its needed effects, atropine/hyoscyamine/phenobarbital/scopolamine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking atropine / hyoscyamine / phenobarbital / scopolamine:

Rare

• Eye pain
• skin rash or hives
• sore throat and fever
• unusual bleeding or bruising
• yellow eyes or skin

Other side effects of Donnatal

Some side effects of atropine / hyoscyamine / phenobarbital / scopolamine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Constipation
• decreased sweating
• dizziness
• dry mouth, nose, throat, or skin

Less common or rare

• Bloated feeling
• blurred vision
• decreased flow of breast milk
• difficult urination
• difficulty in swallowing
• headache
• increased sensitivity of eyes to sunlight
• loss of memory
• nausea or vomiting
• unusual tiredness or weakness

For Healthcare Professionals

Applies to atropine / hyoscyamine / phenobarbital / scopolamine: oral capsule, oral elixir, oral liquid, oral tablet, oral tablet extended release.

Genitourinary

Frequency not reported: Urinary hesitancy and retention, impotence, suppression of lactation^[Ref]

Cardiovascular

Frequency not reported: Tachycardia, palpitation^[Ref]

Ocular

Frequency not reported: Blurred vision, mydriasis, cycloplegia, increased ocular tension^[Ref]

Gastrointestinal

Frequency not reported: Xerostomia, constipation, bloated feeling^[Ref]

Nervous system

Frequency not reported: Loss of taste sense, headache, drowsiness, dizziness, convulsions^[Ref]

Hypersensitivity

Frequency not reported: Severe allergic reaction or drug idiosyncrasies (including anaphylaxis, urticaria, and other dermal manifestations), acquired hypersensitivity (reactions include localized swelling, particularly of eyelids, cheeks, or lips, and erythematous dermatitis)^[Ref]

Musculoskeletal

Frequency not reported: Musculoskeletal pain^[Ref]

Psychiatric

Frequency not reported: Nervousness, insomnia, excitement, delirium, agitation (elderly patients)^[Ref]

Dermatologic

Frequency not reported: Decreased sweating, exfoliative dermatitis (e.g. Stevens-Johnson syndrome, toxic epidermal necrolysis)^[Ref]

Hematologic

Frequency not reported: Megaloblastic anemia^[Ref]

Other

Frequency not reported: Weakness^[Ref]