Summary
Commonly reported side effects of dorzolamide ophthalmic include: burning sensation of eyes, eye discomfort, eye pruritus, local ocular hypersensitivity reaction, stinging of eyes, superficial punctate keratitis, swelling of eye, bitter taste, eye irritation, and eye redness. Other side effects include: blurred vision, lacrimation, photophobia, and xerophthalmia. Continue reading for a comprehensive list of adverse effects.
Applies to dorzolamide ophthalmic: ophthalmic solution.
Serious side effects
Along with its needed effects, dorzolamide ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking dorzolamide ophthalmic:
More common
- Burning, stinging, or discomfort when medicine is applied
- itching, redness, swelling, or other sign of the eye or eyelid irritation
Less common
- Burning, dry, or itching eyes
- discharge from the eye
- excessive tearing
- redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
Rare
- Blood in the urine
- blurred vision
- nausea or vomiting
- pain in the side, back, or abdomen
- skin rash
- tearing
Incidence not known
- Blistering, burning, crusting, dryness, or flaking of the skin
- change in vision
- chills
- cough
- diarrhea
- difficult or labored breathing
- flashes of light
- floaters in vision
- hives or welts
- itching skin
- joint or muscle pain
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- noisy breathing
- redness of the skin
- sore throat
- sores, ulcers, or white spots in the mouth or on the lips
- tightness in the chest
- unusual tiredness or weakness
Get emergency help immediately if any of the following symptoms of overdose occur while taking dorzolamide ophthalmic:
Symptoms of overdose
- Confusion
- irregular heartbeat
- muscle cramps or pain
- numbness, tingling, pain, or weakness in the hands or feet
- seizures
- trembling
- weakness and heaviness of the legs
Other side effects
Some side effects of dorzolamide ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Bitter taste
- feeling of something in the eye
Less common
- Changes in color vision
- difficulty seeing at night
- dryness of the eyes
- eyelid reactions
- headache
- increased sensitivity of the eyes to sunlight
Incidence not known
- Bloody nose
- burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- change in distance vision
- difficulty in focusing the eyes
- dizziness
- dry mouth
- eyelid crusting
- lack or loss of strength
- scaling of the skin
- severe redness, soreness, or swelling of the skin
For Healthcare Professionals
Applies to dorzolamide ophthalmic: ophthalmic solution.
General
The most commonly reported side effects were ocular burning, stinging, or discomfort, and bitter taste.[Ref]
Ocular
Very common (10% or more): Superficial punctate keratitis (up to 15%), burning/stinging
Common (1% to 10%): Tearing, conjunctivitis, eyelid inflammation, eye itching, eyelid irritation, blurred vision
Uncommon (0.1% to 1%): Iridocyclitis
Rare (less than 0.1%): Irritation, pain, eyelid crusting, transient myopia, corneal edema, ocular hypotony, choroidal detachment following filtration surgery[Ref]
Hypersensitivity
Very common (10% or more): Ocular allergic reaction (10%)
Rare (less than 0.1%): Signs and symptoms of local reactions (palpebral reactions) and systemic allergic reactions including angioedema, urticaria, pruritus, rash, shortness of breath, bronchospasm[Ref]
Renal
Rare (less than 0.1%): Urolithiasis[Ref]
Respiratory
Rare (less than 0.1%): Epistaxis
Frequency not reported: Dyspnea[Ref]
Dermatologic
Uncommon (0.1% to 1%): Contact dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis
Rare (less than 0.1%): Skin rash[Ref]
Nervous system
Very common (10% or more): Biter taste (up to 25%)
Frequency not reported: Headache[Ref]
Gastrointestinal
Common (1% to 10%): Nausea
Rare (less than 0.1%): Throat irritation, dry mouth[Ref]
Other
Common (1% to 10%): Asthenia/fatigue[Ref]
