Drug Detail:Amcinonide topical (Amcinonide topical [ am-sin-oh-nide ])
Drug Class: Topical steroids
Usual Adult Dose for Dermatitis
Cream and ointment: Apply a thin film topically to affected area 2 to 3 times a day depending on severity of condition
Lotion: Apply topically and rub into the affected area completely twice a day
Comments:
- Occlusive dressings can be a therapeutic adjunct for the management of psoriasis or recalcitrant conditions.
- If an infection occurs, occlusive dressings should be discontinued and antimicrobial therapy should be initiated.
- The affected area where the drug is applied should be protected from washing, clothing, rubbing until the lotion is dried.
Uses:
- Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses
Usual Adult Dose for Eczema
Cream and ointment: Apply a thin film topically to affected area 2 to 3 times a day depending on severity of condition
Lotion: Apply topically and rub into the affected area completely twice a day
Comments:
- Occlusive dressings can be a therapeutic adjunct for the management of psoriasis or recalcitrant conditions.
- If an infection occurs, occlusive dressings should be discontinued and antimicrobial therapy should be initiated.
- The affected area where the drug is applied should be protected from washing, clothing, rubbing until the lotion is dried.
Uses:
- Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses
Usual Adult Dose for Psoriasis
Cream and ointment: Apply a thin film topically to affected area 2 to 3 times a day depending on severity of condition
Lotion: Apply topically and rub into the affected area completely twice a day
Comments:
- Occlusive dressings can be a therapeutic adjunct for the management of psoriasis or recalcitrant conditions.
- If an infection occurs, occlusive dressings should be discontinued and antimicrobial therapy should be initiated.
- The affected area where the drug is applied should be protected from washing, clothing, rubbing until the lotion is dried.
Uses:
- Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses
Usual Pediatric Dose for Dermatitis
Cream and ointment: Apply a thin film topically to affected area 2 to 3 times a day depending on severity of condition
Lotion: Apply topically and rub into the affected area completely twice a day
Comments:
- Occlusive dressings can be a therapeutic adjunct for the management of psoriasis or recalcitrant conditions.
- If an infection occurs, occlusive dressings should be discontinued and antimicrobial therapy should be initiated.
- The affected area where the drug is applied should be protected from washing, clothing, rubbing until the lotion is dried.
- Administration of topical corticosteroids to pediatric patients should be limited to the least amount compatible with an effective therapeutic regimen.
Uses:
- Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses
Usual Pediatric Dose for Eczema
Cream and ointment: Apply a thin film topically to affected area 2 to 3 times a day depending on severity of condition
Lotion: Apply topically and rub into the affected area completely twice a day
Comments:
- Occlusive dressings can be a therapeutic adjunct for the management of psoriasis or recalcitrant conditions.
- If an infection occurs, occlusive dressings should be discontinued and antimicrobial therapy should be initiated.
- The affected area where the drug is applied should be protected from washing, clothing, rubbing until the lotion is dried.
- Administration of topical corticosteroids to pediatric patients should be limited to the least amount compatible with an effective therapeutic regimen.
Uses:
- Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses
Usual Pediatric Dose for Psoriasis
Cream and ointment: Apply a thin film topically to affected area 2 to 3 times a day depending on severity of condition
Lotion: Apply topically and rub into the affected area completely twice a day
Comments:
- Occlusive dressings can be a therapeutic adjunct for the management of psoriasis or recalcitrant conditions.
- If an infection occurs, occlusive dressings should be discontinued and antimicrobial therapy should be initiated.
- The affected area where the drug is applied should be protected from washing, clothing, rubbing until the lotion is dried.
- Administration of topical corticosteroids to pediatric patients should be limited to the least amount compatible with an effective therapeutic regimen.
Uses:
- Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
Pediatric: Children may absorb proportionally larger amounts after topical application and may be more prone to systemic effects. HPA axis suppression, intracranial hypertension, and Cushing's syndrome have been reported in children receiving topical corticosteroids. Prolonged use may affect growth velocity; growth should be routinely monitored in pediatric patients.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- Contact with the eyes should be avoided.
- The treated area should not be bandaged, covered, or wrapped, as to be occlusive, unless directed by a healthcare provider.
- Parents of pediatric patients should be advised not to use tight-fitting diapers or plastic pants on a child being treated in the diaper area.
Storage requirements:
- Store at room temperature; do not freeze.
Monitoring:
- Endocrine: HPA-axis suppression (Urinary free-cortisol test, ACTH-stimulation test)
Patient advice:
- Patients should report any signs of local adverse reactions, especially those that develop under occlusive dressings.