Drug Detail:Azelastine and fluticasone nasal (Azelastine and fluticasone nasal [ ay-zel-as-teen-and-floo-tik-a-sone ])
Drug Class: Nasal antihistamines and decongestants Nasal steroids
Usual Adult Dose for Allergic Rhinitis
1 spray in each nostril twice a day
Uses: Relief of symptoms of seasonal allergic rhinitis
Usual Pediatric Dose for Allergic Rhinitis
6 years and older:
1 spray in each nostril twice a day
Uses: Relief of symptoms of seasonal allergic rhinitis
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
CONTRAINDICATIONS: Hypersensitivity to any of the ingredients
Safety and efficacy have not been established in patients younger than 6 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- This drug should be administered by the intranasal route only.
- The bottle should be gently shaken before each use.
- This drug should not be sprayed into the eyes. If sprayed into the eyes, they should be flushed with water for at least 10 minutes.
- This drug should be primed before initial use by releasing 6 sprays or until a fine mist appears. When the drug has not been used for 14 or more days, it should be reprimed with 1 spray or until a fine mist appears.
Storage requirements:
- Store upright with the dust cap in place.
- Protect from light.
- Do not store in the freezer or refrigerator.
Monitoring:
- Endocrine: HPA-axis suppression (Urinary free-cortisol test, ACTH-stimulation test)
Patient advice:
- Fatigue, weariness, exhaustion, dizziness or weakness that may also be caused by the disease itself, may occur when using this drug. In these cases, the ability to drive and use machines may be impaired. Alcohol may enhance this effect.