Drug Detail:Beclomethasone nasal (Beclomethasone nasal [ be-kloe-meth-a-sone ])
Drug Class: Nasal steroids
Usual Adult Dose for Allergic Rhinitis
Nasal metered aerosol (80 mcg): 2 nasal aerosol sprays in each nostril once a day (total dose 320 mcg per day)
Maximum dose: 4 nasal aerosol sprays per day
Nasal metered spray (42 mcg): 1 to 2 nasal inhalations (42 to 84 mcg) in each nostril twice a day (168 to 336 mcg/day)
Comments:
- Nasal metered spray: Symptomatic relief usually occurs within a few days after starting therapy; however, in some patients it may take as long as 2 weeks.
- Nasal metered spray should not be continued beyond 3 weeks in the absence of significant symptomatic improvement.
Uses:
- Treatment of the nasal symptoms associated with seasonal and perennial allergic rhinitis
- Relief of the symptoms of nonallergic (vasomotor) rhinitis
- Prevention of recurrence of nasal polyps following surgical removal
Usual Adult Dose for Prevention of Nasal Polyps
Nasal metered aerosol (80 mcg): 2 nasal aerosol sprays in each nostril once a day (total dose 320 mcg per day)
Maximum dose: 4 nasal aerosol sprays per day
Nasal metered spray (42 mcg): 1 to 2 nasal inhalations (42 to 84 mcg) in each nostril twice a day (168 to 336 mcg/day)
Comments:
- Nasal metered spray: Symptomatic relief usually occurs within a few days after starting therapy; however, in some patients it may take as long as 2 weeks.
- Nasal metered spray should not be continued beyond 3 weeks in the absence of significant symptomatic improvement.
Uses:
- Treatment of the nasal symptoms associated with seasonal and perennial allergic rhinitis
- Relief of the symptoms of nonallergic (vasomotor) rhinitis
- Prevention of recurrence of nasal polyps following surgical removal
Usual Pediatric Dose for Allergic Rhinitis
6 to 12 years of age:
Initial dose: Nasal metered spray (42 mcg): 1 to 2 nasal inhalations (42 to 84 mcg) in each nostril twice a day (168 to 336 mcg/day)
Maintenance dose: Nasal metered spray (42 mcg): 1 nasal inhalation (42 mcg) in each nostril twice a day (168 mcg/day)
Maximum dose: Nasal metered spray (42 mcg): 2 nasal inhalations (84 mcg) in each nostril twice a day (336 mcg/day)
12 years and older:
Nasal metered aerosol (80 mcg): 2 nasal aerosol sprays in each nostril once a day (total dose 320 mcg per day)
Maximum dose: 4 nasal aerosol sprays per day
Nasal metered spray (42 mcg): 1 to 2 nasal inhalations (42 to 84 mcg) in each nostril twice a day (168 to 336 mcg/day)
Comments:
- Nasal metered spray: Symptomatic relief usually occurs within a few days after starting therapy; however, in some patients it may take as long as 2 weeks.
- Nasal metered spray should not be continued beyond 3 weeks in the absence of significant symptomatic improvement.
Uses:
- Treatment of the nasal symptoms associated with seasonal and perennial allergic rhinitis
- Relief of the symptoms of nonallergic (vasomotor) rhinitis
- Prevention of recurrence of nasal polyps following surgical removal
Usual Pediatric Dose for Prevention of Nasal Polyps
6 to 12 years of age:
Initial dose: Nasal metered spray (42 mcg): 1 to 2 nasal inhalations (42 to 84 mcg) in each nostril twice a day (168 to 336 mcg/day)
Maintenance dose: Nasal metered spray (42 mcg): 1 nasal inhalation (42 mcg) in each nostril twice a day (168 mcg/day)
Maximum dose: Nasal metered spray (42 mcg): 2 nasal inhalations (84 mcg) in each nostril twice a day (336 mcg/day)
12 years and older:
Nasal metered aerosol (80 mcg): 2 nasal aerosol sprays in each nostril once a day (total dose 320 mcg per day)
Maximum dose: 4 nasal aerosol sprays per day
Nasal metered spray (42 mcg): 1 to 2 nasal inhalations (42 to 84 mcg) in each nostril twice a day (168 to 336 mcg/day)
Comments:
- Nasal metered spray: Symptomatic relief usually occurs within a few days after starting therapy; however, in some patients it may take as long as 2 weeks.
- Nasal metered spray should not be continued beyond 3 weeks in the absence of significant symptomatic improvement.
Uses:
- Treatment of the nasal symptoms associated with seasonal and perennial allergic rhinitis
- Relief of the symptoms of nonallergic (vasomotor) rhinitis
- Prevention of recurrence of nasal polyps following surgical removal
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
- The safety and efficacy of the nasal metered spray in patients younger than 6 years have not been established.
- The safety and efficacy of the nasal metered aerosol in patients younger than 12 years have not been established.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- This drug should be administered by intranasal route only.
- Metered aerosol should be primed prior to initial use by actuating four times. If aerosol is not used for 7 consecutive days it should be primed by spraying 2 times.
- The manufacturer product information should be consulted for proper use.
Storage requirements:
- Consult the manufacturer product information.
General:
Metered aerosol:
- Do not puncture; do not use or store near heat or open flame.
- Do not throw canister into fire or incinerator.
Patient advice:
- Do not exceed the labeled dose amount.
- Avoid spraying into the eyes or mouth.
- Consult your patient leaflet for information regarding how to properly use and store this drug.
- If you have an applicator, check your patient leaflet for proper cleaning of your device.