Drug Detail:Buspirone (Buspirone [ byoo-spye-rone ])
Drug Class: Miscellaneous anxiolytics, sedatives and hypnotics
Usual Adult Dose for Anxiety
- Initial Dose: 7.5 mg orally 2 times a day
- Maintenance Dose: Dosage may be increased 5 mg per day at intervals of 2 to 3 days, as needed.
- Maximum Dose: 60 mg per day
Use: Management of anxiety disorders or the short-term relief of anxiety symptoms.
Renal Dose Adjustments
- Mild to Moderate Renal Impairment: Dose adjustments may be required; however, no specific guidelines have been suggested. Caution is recommended.
- Severe Renal Impairment: Not recommended.
Liver Dose Adjustments
- Mild to Moderate Hepatic Impairment: Dose adjustments may be required; however, no specific guidelines have been suggested. Caution is recommended.
- Severe Hepatic Impairment: Not recommended.
Precautions
Safety and efficacy have not been established in patients younger than 18 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available.
Other Comments
Administration Advice:
- This drug should be taken at the same time each day, and consistently with or without food.
- The usual therapeutic dosage is 15 to 30 mg per day given in divided doses; the dosage should be individualized for each patient.
- The usefulness of this drug should be periodically reassessed if used for extended periods.
General:
- The effectiveness of this drug for more than 3 to 4 weeks has not been demonstrated.
- Overdosage: There is no specific antidote.
- Anxiolytic agents like this drug are not typically used to treat anxiety or tension associated with the stress of everyday life.
Patient Advice:
- Avoid drinking or ingesting any grapefruit products.
- Avoid driving and other potentially dangerous activities such as operating machinery until you know how this drug affects you.