Recommended Dosage

​The recommended dosage of CAPLYTA is 42 mg administered orally once daily with or without food. Dose titration is not required.

Dosage Recommendations for Concomitant Use with Moderate or Strong CYP3A4 Inhibitors

Coadministration with Strong CYP3A4 Inhibitors

​The recommended dosage for patients receiving strong CYP3A4 inhibitors is CAPLYTA 10.5 mg once daily [see Drug Interactions (7.1)].

Coadministration with Moderate CYP3A4 Inhibitors

​The recommended dosage for patients receiving moderate CYP3A4 inhibitors is CAPLYTA 21 mg once daily [see Drug Interactions (7.1)].

Dosage Recommendations for Patients with Hepatic Impairment

​For patients with moderate or severe hepatic impairment (Child-Pugh class B or C), the recommended dosage of CAPLYTA is 21 mg once daily [see Use in Specific Populations (8.6)].