Antiandrogens
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Casodex Dosage

Drug Detail:Casodex (Bicalutamide [ bye-ka-loo-ta-mide ])

Generic Name: BICALUTAMIDE 50mg

Dosage Form: tablet

Drug Class: Antiandrogens Hormones / antineoplastics

Contents
Uses Warnings Before Taking Dosage Side effects Interactions FAQ

Recommended Dose and Schedule

The recommended dose for CASODEX therapy in combination with an LHRH analog is one 50 mg tablet once daily (morning or evening), with or without food. It is recommended that CASODEX be taken at the same time each day. Treatment with CASODEX should be started at the same time as treatment with an LHRH analog. If a dose of CASODEX is missed, take the next dose at the scheduled time. Do not take the missed dose and do not double the next dose.

Dosage Adjustment in Renal Impairment

No dosage adjustment is necessary for patients with renal impairment [see Use in Specific Populations (8.7)].

Dosage Adjustment in Hepatic Impairment

No dosage adjustment is necessary for patients with mild to moderate hepatic impairment. In patients with severe liver impairment (n=4), although there was a 76% increase in the half-life (5.9 and 10.4 days for normal and impaired patients, respectively) of the active enantiomer of bicalutamide no dosage adjustment is necessary [see Use in Specific Populations (8.6)].

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