Drug Detail:Clocortolone topical (Clocortolone topical [ kloe-kor-toe-lone ])
Drug Class: Topical steroids
Usual Adult Dose for Dermatitis
Apply sparingly to the affected areas three times a day and rub in gently
Comments:
- Occlusive dressings may be used; however, if an infection develops, the use of occlusive dressings should be discontinued and anti-microbial therapy initiated.
Use:
- Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses
Usual Adult Dose for Eczema
Apply sparingly to the affected areas three times a day and rub in gently
Comments:
- Occlusive dressings may be used; however, if an infection develops, the use of occlusive dressings should be discontinued and anti-microbial therapy initiated.
Use:
- Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses
Usual Pediatric Dose for Dermatitis
Apply sparingly to the affected areas three times a day and rub in gently
Comments:
- Occlusive dressings may be used; however, if an infection develops, the use of occlusive dressings should be discontinued and anti-microbial therapy initiated.
Use:
- Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses
Usual Pediatric Dose for Eczema
Apply sparingly to the affected areas three times a day and rub in gently
Comments:
- Occlusive dressings may be used; however, if an infection develops, the use of occlusive dressings should be discontinued and anti-microbial therapy initiated.
Use:
- Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
Pediatric: Children may absorb proportionally larger amounts after topical application and may be more prone to systemic effects. HPA axis suppression, intracranial hypertension, and Cushing's syndrome have been reported in children receiving topical corticosteroids. Prolonged use may affect growth velocity; growth should be routinely monitored in pediatric patients.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- Contact with the eyes should be avoided.
- The treated area should not be bandaged, covered, or wrapped, as to be occlusive, unless directed by a healthcare provider.
- Parents of pediatric patients should be advised not to use tight-fitting diapers or plastic pants on a child being treated in the diaper area.
Storage requirements:
- Store at room temperature; do not freeze.
Monitoring:
- Endocrine: HPA-axis suppression (Urinary free-cortisol test, ACTH-stimulation test)
Patient advice:
- Patients should report any signs of local adverse reactions, especially those that develop under occlusive dressings.