Drug Detail:Lotrimin af cream (Clotrimazole topical [ kloe-trim-a-zole ])
Drug Class: Topical antifungals
Usual Adult Dose for Tinea Corporis
Apply clotrimazole topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 4 weeks, depending on the nature and severity of the infection.
Usual Adult Dose for Tinea Cruris
Apply clotrimazole topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 weeks, depending on the nature and severity of the infection.
Usual Adult Dose for Tinea Pedis
Apply clotrimazole topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 4 to 8 weeks, depending on the nature and severity of the infection.
Usual Adult Dose for Cutaneous Candidiasis
Apply clotrimazole topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 to 4 weeks, depending on the nature and severity of the infection.
Usual Adult Dose for Tinea Versicolor
Apply clotrimazole topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 to 4 weeks, depending on the nature and severity of the infection.
Usual Adult Dose for Vaginal Candidiasis
Regimen 1: 100 mg (one 100 mg vaginal suppository) intravaginally once a day for 7 consecutive days alone or in combination with topical application of 1% clotrimazole cream to affected area two times daily for 7 consecutive days.
Regimen 2: 200 mg (one 200 mg vaginal suppository) intravaginally once a day for 3 consecutive days alone or in combination with topical application of 1% clotrimazole cream to affected area two times daily for 7 consecutive days.
Regimen 3: 500 mg (one 500 mg vaginal suppository) intravaginally once.
Regimen 4: One applicatorful of 1% clotrimazole vaginal cream intravaginally once daily (preferably at bedtime) for 7 consecutive days.
Regimen 5: One applicatorful of 2% clotrimazole vaginal cream intravaginally once daily (preferably at bedtime) for 3 consecutive days.
Studies have shown the three and seven day courses of clotrimazole to be equally effective. Patient compliance may be increased with a three day course. Patients who fail to achieve a cure with a single 500 mg dose should be treated with a 3 or 7 day course of clotrimazole.
Weekly or monthly clotrimazole vaginal suppositories appear to be effective topical regimens for chronic suppressive therapy in female patients with HIV.
Usual Pediatric Dose for Tinea Corporis
> 3 years: Apply clotrimazole topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 4 weeks, depending on the nature and severity of the infection.
Usual Pediatric Dose for Tinea Cruris
> 3 years: Apply clotrimazole topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 weeks, depending on the nature and severity of the infection.
Usual Pediatric Dose for Tinea Pedis
> 3 years: Apply clotrimazole topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 4 to 8 weeks, depending on the nature and severity of the infection.
Usual Pediatric Dose for Cutaneous Candidiasis
> 3 years: Apply clotrimazole topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 to 4 weeks, depending on the nature and severity of the infection.
Usual Pediatric Dose for Tinea Versicolor
> 3 years: Apply clotrimazole topical in a quantity sufficient to cover the affected area and immediately surrounding skin twice a day for 2 to 4 weeks, depending on the nature and severity of the infection.
Usual Pediatric Dose for Vaginal Candidiasis
> 12 years: Regimen 1: 100 mg (one 100 mg vaginal suppository) intravaginally once a day for 7 consecutive days alone or in combination with topical application of 1% clotrimazole cream to affected area two times daily for 7 consecutive days.
Regimen 2: 200 mg (one 200 mg vaginal suppository) intravaginally once a day for 3 consecutive days alone or in combination with topical application of 1% clotrimazole cream to affected area two times daily for 7 consecutive days.
Regimen 3: 500 mg (one 500 mg vaginal suppository) intravaginally once.
Regimen 4: One applicatorful of 1% clotrimazole vaginal cream intravaginally once daily (preferably at bedtime) for 7 consecutive days.
Studies have shown the three and seven day courses of clotrimazole to be equally effective. Patient compliance may be increased with a three day course. Patients who fail to achieve a cure with a single 500 mg dose should be treated with a 3 or 7 day course of clotrimazole.
Weekly or monthly clotrimazole vaginal suppositories appear to be effective topical regimens for chronic suppressive therapy in female patients with HIV.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Dialysis
Data not available
Frequently asked questions
- What are the most common skin conditions? (with photos)