Drug Class: Upper respiratory combinations
Usual Adult Dose for Allergic Rhinitis
Dexchlorpheniramine/dextromethorphan/PSE 3.5 mg-30 mg-45 mg/5 mL oral suspension, extended release and Dexchlorpheniramine/dextromethorphan/PSE 3 mg-27.5 mg-50 mg/5 mL oral suspension, extended release:
5 to 15 mL orally every 12 hours not to exceed 30 mL daily.
Usual Adult Dose for Cold Symptoms
Dexchlorpheniramine/dextromethorphan/PSE 3.5 mg-30 mg-45 mg/5 mL oral suspension, extended release and Dexchlorpheniramine/dextromethorphan/PSE 3 mg-27.5 mg-50 mg/5 mL oral suspension, extended release:
5 to 15 mL orally every 12 hours not to exceed 30 mL daily.
Usual Adult Dose for Sinusitis
Dexchlorpheniramine/dextromethorphan/PSE 3.5 mg-30 mg-45 mg/5 mL oral suspension, extended release and Dexchlorpheniramine/dextromethorphan/PSE 3 mg-27.5 mg-50 mg/5 mL oral suspension, extended release:
5 to 15 mL orally every 12 hours not to exceed 30 mL daily.
Usual Pediatric Dose for Allergic Rhinitis
Dexchlorpheniramine/dextromethorphan/PSE 3.5 mg-30 mg-45 mg/5 mL oral suspension, extended release and Dexchlorpheniramine/dextromethorphan/PSE 3 mg-27.5 mg-50 mg/5 mL oral suspension, extended release:
2 to 5 years: 1.25 to 2.5 mL orally every 12 hours not to exceed 5 mL daily.
6 to 11 years: 2.5 to 5 mL orally every 12 hours not to exceed 10 mL daily.
12 years or older: 5 to 15 mL orally every 12 hours not to exceed 30 mL daily.
Usual Pediatric Dose for Cold Symptoms
Dexchlorpheniramine/dextromethorphan/PSE 3.5 mg-30 mg-45 mg/5 mL oral suspension, extended release and Dexchlorpheniramine/dextromethorphan/PSE 3 mg-27.5 mg-50 mg/5 mL oral suspension, extended release:
2 to 5 years: 1.25 to 2.5 mL orally every 12 hours not to exceed 5 mL daily.
6 to 11 years: 2.5 to 5 mL orally every 12 hours not to exceed 10 mL daily.
12 years or older: 5 to 15 mL orally every 12 hours not to exceed 30 mL daily.
Usual Pediatric Dose for Sinusitis
Dexchlorpheniramine/dextromethorphan/PSE 3.5 mg-30 mg-45 mg/5 mL oral suspension, extended release and Dexchlorpheniramine/dextromethorphan/PSE 3 mg-27.5 mg-50 mg/5 mL oral suspension, extended release:
2 to 5 years: 1.25 to 2.5 mL orally every 12 hours not to exceed 5 mL daily.
6 to 11 years: 2.5 to 5 mL orally every 12 hours not to exceed 10 mL daily.
12 years or older: 5 to 15 mL orally every 12 hours not to exceed 30 mL daily.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
The FDA has not approved use of over-the-counter cough and cold medications to children aged less than 2 years, and proper dosing for children in this age group has not been studied. Clinicians should be aware of the risk for serious illness or fatal overdose from administration of cough and cold medications to children aged less than 2 years. Clinicians should be certain that caregivers understand 1) the importance of administering cough and cold medications only as directed and 2) the risk for overdose if they administer additional medications that might contain the same ingredient.
Dialysis
Data not available
