Drug Detail:Trispec dmx (Dextromethorphan and guaifenesin [ dex-troe-me-thor-fan-and-gwye-fen-e-sin ])
Drug Class: Upper respiratory combinations
Usual Adult Dose for Cough
Dose referred to by strength of dextromethorphan/guaiFENesin (in mg) per unit of measurement:
10/100 per 5 mL: 10 mL every 4 hours, maximum 6 doses per day
10/187 per 5 mL: 10 mL every 4 hours, maximum 4 doses per day
10/200 per 5 mL: 10 mL every 4 hours, maximum 6 doses per day
20/400 per 5 mL: 5 mL every 4 hours, maximum 6 doses per day
20/200 per 10 mL: 10 mL every 4 hours, maximum 6 doses per day
20/200 per 20 mL: 20 mL every 4 hours, maximum 6 doses per day
20/400 per 20 mL: 20 mL every 4 hours, maximum 6 doses per day
Oral solids (tablets/caplets/capsule/gel caps):
10/200 per caplet: 1 or 2 every 4 hours, maximum 12 caplets per day
20/400 per tablet: 1 tablet every 4 hours, maximum 6 doses per day
30/600 per tablet: 1 to 2 tablets every 12 hours, maximum 4 tablets per day
60/1200 per tablet: 1 to 2 tablets every 12 hours, maximum 4 tablets per day
Usual Pediatric Dose for Cough
Dose referred to by strength of dextromethorphan/guaiFENesin (in mg) per unit of measurement:
10/100 per 5 mL:
12 years and older: 10 mL every 4 hours, maximum 6 doses per day
10/187 per 5 mL:
12 years and older: 10 mL every 4 hours, maximum 4 doses per day
6 to under 12 years: 5 mL every 4 hours, maximum 4 doses per day
2 to under 6 years: 2.5 mL every 4 hours, maximum 4 doses per day
10/200 per 5 mL:
12 years and older: 10 mL every 4 hours, maximum 6 doses per day
20/400 per 5 mL 12 years and older: 5 mL every 4 hours, maximum 6 doses per day
20/200 per 10 mL
12 years and older: 10 mL every 4 hours, maximum 6 doses per day
20/200 per 20 mL:
12 years and older: 20 mL every 4 hours, maximum 6 doses per day
20/400 per 20 mL:
12 years and older: 20 mL every 4 hours, maximum 6 doses per day
Oral solids (tablets/caplets/capsule/gel caps):
10/200 per caplet:
12 years and older: 1 or 2 every 4 hours, maximum 12 caplets per day
20/400 per tablet:
12 years and older: 1 tablet every 4 hours, maximum 6 doses per day
30/600 per tablet:
12 years and older: 1 to 2 tablets every 12 hours, maximum 4 tablets per day
60/1200 per tablet:
12 years and older: 1 to 2 tablets every 12 hours, maximum 4 tablets per day
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
CONTRAINDICATIONS:
- Current use of a monoamine oxidase inhibitor (MAOI) or use within 14 days of stopping a MAOI.
Safety and efficacy have not been established in patients younger than 2 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
