Drug Detail:Dytan-d (Diphenhydramine and phenylephrine [ dye-fen-hye-dra-meen-and-fen-il-eff-rin ])
Drug Class: Upper respiratory combinations
Usual Adult Dose for Allergic Rhinitis
Diphenhydramine 12.5 mg / phenylephrine 5 mg per 10 mL liquid: 20 mL every 4 hours
Maximum dose: 6 doses per 24 hours
Diphenhydramine 25 mg / phenylephrine 10 mg per tablet: 1 tablet every 4 hours
Maximum dose: 6 doses per 24 hours
Usual Adult Dose for Cold Symptoms
Diphenhydramine 12.5 mg / phenylephrine 5 mg per 10 mL liquid: 20 mL every 4 hours
Maximum dose: 6 doses per 24 hours
Diphenhydramine 25 mg / phenylephrine 10 mg per tablet: 1 tablet every 4 hours
Maximum dose: 6 doses per 24 hours
Usual Pediatric Dose for Allergic Rhinitis
Diphenhydramine 6.25 mg / phenylephrine 2.5 mg per 5 mL liquid:
6 to under 12 years: 10 mL every 4 hours
Maximum dose: 6 doses per 24 hours
Diphenhydramine 12.5 mg / phenylephrine 5 mg per 10 mL liquid:
12 years and older: 20 mL every 4 hours
6 to under 12 years: 10 mL every 4 hours
Maximum dose: 6 doses per 24 hours
Diphenhydramine 25 mg / phenylephrine 10 mg per tablet:
12 years and older: 1 tablet every 4 hours
Maximum dose: 6 doses per 24 hours
Usual Pediatric Dose for Cold Symptoms
Diphenhydramine 6.25 mg / phenylephrine 2.5 mg per 5 mL liquid:
6 to under 12 years: 10 mL every 4 hours
Maximum dose: 6 doses per 24 hours
Diphenhydramine 12.5 mg / phenylephrine 5 mg per 10 mL liquid:
12 years and older: 20 mL every 4 hours
6 to under 12 years: 10 mL every 4 hours
Maximum dose: 6 doses per 24 hours
Diphenhydramine 25 mg / phenylephrine 10 mg per tablet:
12 years and older: 1 tablet every 4 hours
Maximum dose: 6 doses per 24 hours
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
CONTRAINDICATIONS:
- Current use of a monoamine oxidase inhibitor (MAOI) or use within 14 days of stopping a MAOI.
- Concomitant use with any other diphenhydramine-containing products, including topical preparations.
Safety and efficacy have not been established in patients younger than 6 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- Use provided measuring cups for dosing.
Patient advice:
- Take only as directed.
- Avoid drinking alcohol while on this drug.
- Discontinue for nervousness, dizziness, or sleepiness.
- Use caution if driving a motor vehicle or operating machinery.
- If symptoms last over 7 days or are accompanied by fever, seek medical attention.
- If cough lasts over 7 days or comes back, or is accompanied or followed by fever, headache that lasts, or rash, seek medical care promptly.
