Usual Adult Dose for Esophageal Varices

Initial dose: 1.5 to 5.0 mL IV per varix up to a maximum of 20 mL per treatment session

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Consider the lowest possible effective dose in patients with severe hepatic dysfunction (Child Class C).

Precautions

Submucosal injections are not recommended.

Consider the lowest possible effective dose in patients with concomitant cardiorespiratory disease.

Safety and efficacy in pediatric patients have not been established.

Dialysis

Data not available

Other Comments

Follow-up injections to obliterate the varix should be administered at one week, six weeks, three months, and six months as needed.

Ethanolamine oleate has no effect upon portal hypertension, the cause of esophageal varices. Recanalization and collateralization may occur, necessitating reinjection.

The maximum volume per session should not be exceeded to avoid possible anaphylaxis and severe necrosis.