Usual Adult Dose for Steroid Responsive Inflammatory Conditions

Fluorometholone 0.1%/0.25% suspension: 1 drop into the conjunctival sac 2 to 4 times per day

Fluorometholone acetate suspension: 1 to 2 drops instilled into the conjunctival sac(s) 4 times per day

Ointment: A small amount (approximately 1.5 inch ribbon) of ointment should be applied to the conjunctival sac 1 to 3 times per day

Comments:

• Fluorometholone acetate: During the initial 24 to 48 hours, the dosage may be safely increased to 2 drops every 2 hours.
• Fluorometholone ophthalmic suspension and ointment: During the initial 24 to 48 hours, the dosing frequency may be increased to 1 application every 4 hours.
• Withdrawal of treatment should be carried out by gradually decreasing the frequency of applications.
• If signs and symptoms fail to improve after 2 days, the patient should be re-evaluated.

• Treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe.

Usual Pediatric Dose for Steroid Responsive Inflammatory Conditions

2 years or older:
Fluorometholone 0.1%/0.25% suspension: 1 drop into the conjunctival sac 2 to 4 times per day

Ointment: A small amount (approximately 1.5 inch ribbon) of ointment should be applied to the conjunctival sac 1 to 3 times per day

Comments:

• Fluorometholone acetate: During the initial 24 to 48 hours, the dosage may be safely increased to 2 drops every 2 hours.
• Fluorometholone ophthalmic suspension and ointment: During the initial 24 to 48 hours, the dosing frequency may be increased to 1 application every 4 hours.
• Withdrawal of treatment should be carried out by gradually decreasing the frequency of applications.
• If signs and symptoms fail to improve after 2 days, the patient should be re-evaluated.

• Treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Fluorometholone 0.1%/0.25% suspension and ointment: Safety and efficacy have not been established in patients younger than 2 years.

Fluorometholone acetate: Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Bottle should be shaken before use.

• Care should be taken to avoid touching the applicator tip to the eye or to any other surface.
• In order to minimize systemic absorption of eye drops, pressure should be applied to the tear duct immediately following administration of the drug.

• Do not freeze
• Store in an upright position