Drug Detail:Formoterol and glycopyrrolate (Formoterol and glycopyrrolate [ for-moe-ter-ol-and-glye-koe-pir-oh-late ])
Drug Class: Bronchodilator combinations
Usual Adult Dose for Chronic Obstructive Pulmonary Disease - Maintenance
2 inhalations orally twice a day, in the morning and in the evening
Maximum dose: 2 inhalations twice daily
Comments:
- Two inhalations of formoterol 4.8 mcg-glycopyrrolate 9 mcg equal one dose.
Uses: Long-term, maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema
Renal Dose Adjustments
No adjustment recommended.
Liver Dose Adjustments
No adjustment recommended.
Precautions
CONTRAINDICATIONS:
- Use of a long-acting beta-2 (LABA) agonist without an inhaled corticosteroid (ICS) in asthma patients; this drug is not indicated for asthma treatment
- Hypersensitivity to any of the ingredients
Safety and efficacy have not been established in patients younger than 18 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- For oral inhalation only.
- Priming the inhalation device before using for the first time to ensure appropriate drug content in each actuation. The manufacturer product information should be consulted for additional instructions for its use.
- Shake well before using.
Missed dose:
- If a dose is missed, take the next dose at the usual time.
- Do not use more often or more puffs than prescribed.
Storage requirements:
- Store at controlled room temperature 20C to 25C (68F to 77F)
- The canister should be at room temperature before use
Limitations of use:
- This drug is not indicated for the relief of acute bronchospasm or for the treatment of asthma.
Patient advice:
- Patients should read the medication guide and instructions for the use of this drug.
- A rescue inhaler should be provided to patients to treat acute symptoms. Patients should be instructed on how to use the rescue inhaler.
- Seek medical attention immediately if symptoms get worse, or if more inhalations than usual of their rescue inhaler are needed.
- Therapy should not be stopped without physician/provider guidance since symptoms may recur after discontinuation.
- Discontinue previous regular use of short acting beta2-agonist and use them only for the symptomatic relief of acute symptoms.
