Usual Adult Dose for Pruritus

Topical cream or topical lotion: Apply a thin film to affected area 2 to 3 times daily depending on the severity of the condition.

Rectal cream: Twice daily, fill applicator and insert gently into anal area. Gently squeeze applicator until cream has covered all areas of discomfort.

Usual Adult Dose for Hemorrhoids

Topical cream or topical lotion: Apply a thin film to affected area 2 to 3 times daily depending on the severity of the condition.

Rectal cream: Twice daily, fill applicator and insert gently into anal area. Gently squeeze applicator until cream has covered all areas of discomfort.

Usual Pediatric Dose for Pruritus

Apply (topical cream or topical lotion) amount commensurate with age, body weight and physical condition to affected area as directed by physician.

Usual Pediatric Dose for Hemorrhoids

Apply (topical cream or topical lotion) amount commensurate with age, body weight and physical condition to affected area as directed by physician.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushings's syndrome, hyperglycemia, and glycosuria in some patients.

Pediatric patients may demonstrate greater susceptibility to topical corticosteroid induced HPA axis suppression and Cushing's syndrome due to the larger skin surface area to body weight ratio.

Safety and effectiveness of the rectal cream have not been established in pediatric patients (less than 18 years of age).

Dialysis

Data not available

Other Comments

Some rectal cream products provide single-use cleansing wipes to be used to clean the affected area prior to application of the cream.

Rectal cream tubes and applicators should not be completely inserted into the anus or deep into the rectum.