By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo

TheMediTary.Com

Medical Information, Documents, News - TheMediTary.Com

  • Home
  • News
  • Drugs
  • Drugs A-Z
  • Medical Answers
  • About Us
  • Contact
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo
Search Drugs
  • Drugs
    • Latest Drugs
    • Drugs A-Z
    • Medical Answers
  • News
    • FDA Alerts
    • Medical News
    • Health
    • Consumer Updates
    • Children's Health
  • More TheMediTary.Com
    • About Us
    • Contact
Follow US
Home > Drugs > Immune globulins > Kedrab (human) > Kedrab Dosage
Immune globulins
https://themeditary.com/dosage-information/kedrab-dosage-4689.html

Kedrab Dosage

Drug Detail:Kedrab (human) (Rabies immune globulin (human) (test))

Generic Name: Human Rabies Virus Immune Globulin 150[iU] in 1mL

Dosage Form: injection, solution

Drug Class: Immune globulins

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

For wound infiltration and intramuscular use.

Dosage

Post-exposure prophylaxis consists of a single 20 IU/kg body weight dose of KEDRAB and a full course of rabies vaccine (See Table 1).

Table 1: Rabies Post-exposure Prophylaxis Schedule*

* Adapted from reference 1.

† These regimens are applicable for all age groups, including children.

ǂ Day 0 is the day the first dose of vaccine is administered. Refer to vaccine manufacturer's instructions or to the recommendations of the Advisory Committee on Immunization Practices (ACIP)1,2 for appropriate rabies vaccine formulations, schedules, and dosages.

§ Any person with a history of rabies vaccination and a documented history of antibody response to the prior vaccination.

Vaccination Status Intervention Regimen†
Not previously
vaccinated
Wound Cleansing
  • Cleanse all wounds immediately and thoroughly with soap and water.
  • Irrigate the wounds with a viricidal agent such as a povidone-iodine solution, if available.
KEDRAB® 20 IU/kg body weight
  • Administer KEDRAB as soon as possible after exposure, preferably at the time of the first rabies vaccine dose. However, should a delay occur, administer KEDRAB at any time up to and including seven days after the first dose of rabies vaccine.
  • If there is a delay, initiate post-exposure prophylaxis at any time after exposure.
  • Infiltrate the area around and into the wound(s), if anatomically feasible, with the full dose of KEDRAB.
  • Inject the remainder, if any, intramuscularly at an anatomical site distant from the site of rabies vaccine administration.
  • Do not exceed the recommended dose of KEDRAB because this can partially suppress active production of rabies virus antibodies. [see Drug Interactions (7)]
  • Do not administer additional doses of KEDRAB, even if the antibody response to vaccination is delayed. (7)
  • Use separate syringes, needles, and anatomical injection sites for KEDRAB and for rabies vaccine.
Rabies Vaccine
  • Administer rabies vaccine on Day 0 and on subsequent vaccine administration daysǂ at an anatomical site that is distant from the KEDRAB administration site(s).
  • Complete a rabies vaccination series
Previously vaccinated§ Wound cleansing
  • Cleanse all wounds immediately and thoroughly with soap and water.
  • Irrigate the wounds with a viricidal agent such as povidone-iodine solution if available.
KEDRAB®
  • Do not administer KEDRAB. [see Warnings and Precautions (5.1)]
Rabies Vaccine
  • Administer rabies vaccine on Day 0.ǂ
  • Complete a rabies vaccination series for previously vaccinated persons.†
Other Considerations Tetanus prophylaxis and/or antibiotics
  • Provide treatment if medically indicated

Administration

Infiltrate as much of the KEDRAB dose as possible into and around any detectable bite wounds if infiltration at the bite site is feasible. Administer any remaining KEDRAB intramuscularly into anatomical site(s) distant from the site of the rabies vaccine.

  • When the bite site is unknown or indeterminate (undetectable) or if infiltration is difficult at the bite site (e.g., lips, fingers, knee), administer the full KEDRAB dose by the intramuscular route at a site distant from the site of rabies vaccination.
  • If a large intramuscular volume is required (>2 mL for children or >5 mL for adults), administer the total volume in divided doses at different sites.
  • Do not mix KEDRAB with the rabies vaccine or administer in the same syringe with the rabies vaccine.
  • Discard unused portion of the product in the vial.

​Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration. Do not use if either of these conditions exists, and contact Kedrion Biopharma Inc. at 1-855-353-7466. Do not discard the vial.

Share this Article
Latest News
Medical News

Aging and longevity: What role might coffee play?

Jun 02, 2025
Seed oils: Omega-6 fatty acids may lower diabetes, heart disease risk
Type 2 diabetes: Sugary drinks may significantly raise risk
COVID-19: Who do the new vaccine guideline changes affect?
Vitamin D supplements may help slow down aging by 3 years
Aging: Exercise timing, consistency can affect heart and lung fitness
Related Drugs
Fidanacogene Elaparvovec
Cerave Anti-Itch
Centrum Adult
Crovalimab
Cyltezo Prefilled Syringe
Zepbound Pen
Mylanta One
Uretron Ds
Medihoney Wound And Burn Dressing
Lidotrode

Other drugs

Name Drug Class Updated
Fidanacogene Elaparvovec Drugs 03-Oct-2024
Cerave Anti-Itch Drugs 02-Oct-2024
Centrum Adult Drugs 02-Oct-2024
Crovalimab Drugs 02-Oct-2024
Cyltezo Prefilled Syringe Drugs 01-Oct-2024
Zepbound Pen Drugs 30-Sep-2024
Mylanta One Drugs 27-Sep-2024
Uretron Ds Drugs 27-Sep-2024
Medihoney Wound And Burn Dressing Drugs 26-Sep-2024
Lidotrode Drugs 26-Sep-2024
Libervant Drugs 26-Sep-2024
Moderna Covid-19 Drugs 25-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024

Categories

  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health

About US

Welcome to TheMediTary.Com

Our website provides reliable and up-to-date information on various medical topics. We empower individuals to take charge of their health by simplifying complex medical jargon and providing practical tips and advice. We prioritize the privacy and confidentiality of our users and welcome feedback to improve our services.

Website use data of FDA and other sources

DMCA.com Protection Status Truste Protection Status Trust Mark Protection Status
HONcode logo We comply with the HONcode standard for trustworthy health information.
Quick Link
  • About Us
  • Contact Us
  • Editorial Policy
  • Privacy Policy
  • Accessibility Policy
  • Terms & Conditions
  • Disclaimer
  • DMCA
  • Do Not Sell My Personal Information
  • Sitemap
  • Care Notes
  • Health Guide
  • Professional
Drugs
  • New Drugs
  • Medical Answers
  • Drugs A-Z
  • Drug Classes
  • Drug Dosage
  • Pill Identifier
  • Consumer Infor
  • Side Effects
  • Inactive Ingredients
  • Pregnancy Warnings
  • Patient Tips
  • Treatments
News
  • Latest News
  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health
Find US
  • Medium
  • Google Site
  • Blogspot
  • API
  • Reddit
  • Tumblr
  • Scoop.it
  • Substack
  • Wordpress
  • Wix
  • Behance

© 2025 TheMediTary.Com All rights reserved. Operated by