Drug Detail:Loteprednol (ophthalmic) (Loteprednol (ophthalmic) [ lo-te-pred-nol-off-thal-mik ])
Drug Class: Ophthalmic steroids
Usual Adult Dose for Seasonal Allergic Conjunctivitis
0.2% suspension: 1 drop instilled into the affected eye(s) four times per day
Comments:
- Shake well before using.
Use: Temporary relief of the signs and symptoms of seasonal allergic conjunctivitis
Usual Adult Dose for Acne Rosacea
0.5% suspension:1 to 2 drops instilled into the conjunctival sac of the affected eye four times per day
Comments:
- Shake well before using.
- During the initial treatment within the first week, the dosing may be increased, up to 1 drop every hour, if needed.
- Care should be taken not to discontinue therapy prematurely.
- If signs and symptoms fail to improve after two days, the patient should be re-evaluated.
Use: Treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe such as allergic conjunctivitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, selected infective conjunctivitis, when the inherent hazard of steroid use is accepted to obtain an advisable diminution in edema and inflammation
Usual Adult Dose for Iritis
0.5% suspension:1 to 2 drops instilled into the conjunctival sac of the affected eye four times per day
Comments:
- Shake well before using.
- During the initial treatment within the first week, the dosing may be increased, up to 1 drop every hour, if needed.
- Care should be taken not to discontinue therapy prematurely.
- If signs and symptoms fail to improve after two days, the patient should be re-evaluated.
Use: Treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe such as allergic conjunctivitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, selected infective conjunctivitis, when the inherent hazard of steroid use is accepted to obtain an advisable diminution in edema and inflammation
Usual Adult Dose for Keratitis
0.5% suspension:1 to 2 drops instilled into the conjunctival sac of the affected eye four times per day
Comments:
- Shake well before using.
- During the initial treatment within the first week, the dosing may be increased, up to 1 drop every hour, if needed.
- Care should be taken not to discontinue therapy prematurely.
- If signs and symptoms fail to improve after two days, the patient should be re-evaluated.
Use: Treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe such as allergic conjunctivitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, selected infective conjunctivitis, when the inherent hazard of steroid use is accepted to obtain an advisable diminution in edema and inflammation
Usual Adult Dose for Conjunctivitis
0.5% suspension:1 to 2 drops instilled into the conjunctival sac of the affected eye four times per day
Comments:
- Shake well before using.
- During the initial treatment within the first week, the dosing may be increased, up to 1 drop every hour, if needed.
- Care should be taken not to discontinue therapy prematurely.
- If signs and symptoms fail to improve after two days, the patient should be re-evaluated.
Use: Treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe such as allergic conjunctivitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, selected infective conjunctivitis, when the inherent hazard of steroid use is accepted to obtain an advisable diminution in edema and inflammation
Usual Adult Dose for Cyclitis
0.5% suspension:1 to 2 drops instilled into the conjunctival sac of the affected eye four times per day
Comments:
- Shake well before using.
- During the initial treatment within the first week, the dosing may be increased, up to 1 drop every hour, if needed.
- Care should be taken not to discontinue therapy prematurely.
- If signs and symptoms fail to improve after two days, the patient should be re-evaluated.
Use: Treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe such as allergic conjunctivitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, selected infective conjunctivitis, when the inherent hazard of steroid use is accepted to obtain an advisable diminution in edema and inflammation
Usual Adult Dose for Postoperative Ocular Inflammation
0.5% ointment: A small amount (approximately 0.5 inch ribbon) should be applied into the conjunctival sac(s) four times per day beginning 24 hours after surgery and continuing throughout the first 2 weeks of the post-operative period
0.5% gel/0.5% suspension: 1 to 2 drops should be applied into the conjunctival sac of the affected eye four times per day beginning 24 hours after surgery and continuing throughout the first 2 weeks of the post-operative period
Comments:
- 0.5% gel: Invert closed bottle and shake once to fill tip before instilling drops.
- 0.5% suspension: Shake well before using.
Use: Treatment of post-operative inflammation following ocular surgery
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
Safety and efficacy have not been established in patients younger than 18 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Storage requirements:
- Do not freeze
- Store the container in an upright position