Drug Detail:Naftifine topical (Naftifine topical [ naf-ti-feen-top-ik-al ])
Drug Class: Topical antifungals
Usual Adult Dose for Tinea Corporis
1% CREAM: A sufficient quantity should be gently massaged into the affected and surrounding skin areas once a day.
1% GEL: A sufficient quantity should be gently massaged into the affected and surrounding skin areas twice a day in the morning and evening.
2% CREAM: A thin layer should be applied to the affected areas plus a 1/2 inch margin of healthy surrounding skin once a day for 2 weeks.
Uses:
1% CREAM: For the topical treatment of tinea cruris and tinea corporis due to T rubrum, T mentagrophytes, and Epidermophyton floccosum
1% GEL: For the topical treatment of tinea cruris and tinea corporis due to T rubrum, T mentagrophytes, T tonsurans, and E floccosum
2% CREAM: For the treatment of tinea cruris and tinea corporis due to Trichophyton rubrum
Usual Adult Dose for Tinea Cruris
1% CREAM: A sufficient quantity should be gently massaged into the affected and surrounding skin areas once a day.
1% GEL: A sufficient quantity should be gently massaged into the affected and surrounding skin areas twice a day in the morning and evening.
2% CREAM: A thin layer should be applied to the affected areas plus a 1/2 inch margin of healthy surrounding skin once a day for 2 weeks.
Uses:
1% CREAM: For the topical treatment of tinea cruris and tinea corporis due to T rubrum, T mentagrophytes, and Epidermophyton floccosum
1% GEL: For the topical treatment of tinea cruris and tinea corporis due to T rubrum, T mentagrophytes, T tonsurans, and E floccosum
2% CREAM: For the treatment of tinea cruris and tinea corporis due to Trichophyton rubrum
Usual Adult Dose for Tinea Pedis
1% CREAM: A sufficient quantity should be gently massaged into the affected and surrounding skin areas once a day.
1% GEL: A sufficient quantity should be gently massaged into the affected and surrounding skin areas twice a day in the morning and evening.
2% CREAM: A thin layer should be applied to the affected areas plus a 1/2 inch margin of healthy surrounding skin once a day for 2 weeks.
2% GEL: A thin layer should be applied to the affected areas plus an approximate 1/2 inch margin of healthy surrounding skin once a day for 2 weeks.
Uses:
1% CREAM: For the topical treatment of tinea pedis due to T rubrum, T mentagrophytes, and E floccosum
1% GEL: For the topical treatment of tinea pedis due to T rubrum, T mentagrophytes, T tonsurans, and E floccosum
2% CREAM: For the treatment of interdigital tinea pedis due to T rubrum
2% GEL: For the treatment of interdigital tinea pedis due to T rubrum, T mentagrophytes, and E floccosum
Usual Pediatric Dose for Tinea Corporis
2 years or older:
2% CREAM: A thin layer should be applied to the affected areas plus a 1/2 inch margin of healthy surrounding skin once a day for 2 weeks.
Uses: For the treatment of tinea corporis due to T rubrum
Usual Pediatric Dose for Tinea Cruris
12 years or older:
2% CREAM: A thin layer should be applied to the affected areas plus a 1/2 inch margin of healthy surrounding skin once a day for 2 weeks.
Use: For the treatment of tinea cruris due to T rubrum
Usual Pediatric Dose for Tinea Pedis
12 years or older:
2% CREAM: A thin layer should be applied to the affected areas plus a 1/2 inch margin of healthy surrounding skin once a day for 2 weeks.
2% GEL: A thin layer should be applied to the affected areas plus an approximate 1/2 inch margin of healthy surrounding skin once a day for 2 weeks.
Uses:
2% CREAM: For the treatment of interdigital tinea pedis due to T rubrum
2% GEL: For the treatment of interdigital tinea pedis due to T rubrum, T mentagrophytes, and E floccosum
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
CONTRAINDICATIONS:
- Hypersensitivity to any of the ingredients (1% cream and gel)
- None (2% cream and gel)
1% Cream and Gel: Safety and efficacy have not been established in patients younger than 18 years.
2% Cream:
- Treatment of tinea corporis: Safety and efficacy have not been established in patients younger than 2 years.
- Treatment of tinea cruris and interdigital tinea pedis: Safety and efficacy have not been established in patients younger than 12 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- Wash hands after application.
- Only use topically; not for ophthalmic, oral, or intravaginal use.
General:
- Diagnosis of the disease should be confirmed by direct microscopic examination or by culture.
- Patients should be reevaluated if no clinical improvement is seen after 4 weeks of therapy with the 1% formulations.
Patient advice:
- Keep this drug away from the eyes, nose, mouth, and other mucous membranes.
- Consult the physician if irritation or sensitivity develops after use.