Drug Detail:Alinia (Nitazoxanide [ nye-ta-zox-a-nide ])
Drug Class: Amebicides
Usual Adult Dose for Cryptosporidiosis
500 mg orally every 12 hours for 3 days
Use: For the treatment of diarrhea due to Giardia lamblia or Cryptosporidium parvum
Usual Adult Dose for Giardiasis
500 mg orally every 12 hours for 3 days
Use: For the treatment of diarrhea due to Giardia lamblia or Cryptosporidium parvum
Usual Pediatric Dose for Cryptosporidiosis
1 to 3 years: 100 mg orally every 12 hours
4 to 11 years: 200 mg orally every 12 hours
12 years or older: 500 mg orally every 12 hours
Duration of Therapy: 3 days
Use: For the treatment of diarrhea due to G lamblia or C parvum
Usual Pediatric Dose for Giardiasis
1 to 3 years: 100 mg orally every 12 hours
4 to 11 years: 200 mg orally every 12 hours
12 years or older: 500 mg orally every 12 hours
Duration of Therapy: 3 days
Use: For the treatment of diarrhea due to G lamblia or C parvum
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
CONTRAINDICATIONS:
Prior hypersensitivity to the active component or any of the ingredients
Safety and efficacy have not been established in patients younger than 1 year.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- Administer with food.
- Do not use the tablets for pediatric patients 11 years or younger.
- Shake the oral suspension well before each use; discard unused oral suspension after 7 days.
Storage requirements:
- Oral suspension:
- Unsuspended powder: Store at 25C (77F); excursions permitted to 15C to 30C (59F to 86F).
- Reconstituted suspension: May store for 7 days at room temperature; keep bottle tightly closed.
- Tablets: Store at 25C (77F); excursions permitted to 15C to 30C (59F to 86F).
Reconstitution/preparation techniques:
- Oral suspension: The manufacturer product information should be consulted.
General:
- Limitations of Use: Efficacy for the treatment of diarrhea due to C parvum has not been established in HIV-infected or immunodeficient patients.