Insulin
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Novolin N Dosage

Drug Detail:Novolin n (Insulin isophane [ in-soo-lin-eye-soe-fane ])

Generic Name: INSULIN HUMAN 100[iU] in 1mL

Dosage Form: injection, suspension

Drug Class: Insulin

Contents
Uses Warnings Before Taking Dosage Side effects Interactions FAQ

Important Administration Instructions

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Always check insulin labels before administration [see Warnings and Precautions (5.4)].
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NOVOLIN N is a suspension that must be resuspended immediately before use. Resuspension is easier when the insulin has reached room temperature.
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To resuspend vial, roll the vial gently in your hands in a horizontal position 10 times until the suspension appears uniformly white and cloudy. Inject immediately.
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To resuspend FlexPen, gently move the pen up and down 20 times so the glass ball moves from one end of the cartridge to the other until the suspension appears uniformly white and cloudy. Inject immediately.
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Inspect NOVOLIN N visually before use. Do not use NOVOLIN N if discoloration or particulate matter is seen.
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Administer NOVOLIN N by subcutaneous injection in the abdominal wall, thigh, upper arm, or buttocks.
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Rotate the injection site within the same region from one injection to the next to reduce the risk of ​lipodystrophy and localized cutaneous amyloidosis. Do not inject into areas of lipodystrophy or localized cutaneous amyloidosis [see Warnings and Precautions (5.2), Adverse Reactions (6)].
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​During changes to a patient’s insulin regimen, increase the frequency of blood glucose monitoring [see Warnings and Precautions (5.2)].
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Do not administer NOVOLIN N intravenously or intramuscularly and do not use in an insulin infusion pump.

Dosage Information

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Individualize and adjust the dosage of NOVOLIN N based on the individual's metabolic needs, blood glucose monitoring results and glycemic control goal.
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Administer NOVOLIN N once or twice daily.
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In patients with type 1 diabetes, NOVOLIN N should generally be used in regimens that include a short-acting insulin.
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Dosage adjustments may be needed with changes in physical activity, changes in meal patterns (i.e., macronutrient content or timing of food intake), changes in renal or hepatic function or during acute illness [see Warnings and Precautions (5.2, 5.3) and Use in Specific Populations (8.6, 8.7)].
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Dosage adjustment may be needed when switching from another insulin to NOVOLIN N [see Warnings and Precautions (5.2)].

Dosage Adjustment due to Drug Interactions

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Dosage adjustment may be needed when NOVOLIN N is co-administered with certain drugs [see Drug Interactions (7)].

Instructions for Mixing with Other Insulins

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NOVOLIN N can be mixed in the same syringe with regular human insulin.
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When mixing, the regular human insulin should be drawn into the syringe first, followed by the NOVOLIN N. The mixture should be injected immediately after mixing.
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