Atypical antipsychotics
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Nuplazid Dosage

Drug Detail:Nuplazid (Pimavanserin [ pim-a-van-ser-in- ])

Generic Name: pimavanserin tartrate 34mg

Dosage Form: tablet, coated

Drug Class: Atypical antipsychotics

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

Recommended Dosage

The recommended dose of NUPLAZID is 34 mg taken orally once daily, without titration.

Administration Information

NUPLAZID can be taken with or without food [see Clinical Pharmacology (12.3)].

​NUPLAZID capsules can be taken whole, or opened and the entire contents sprinkled over a tablespoon (15 mL) of applesauce, yogurt, pudding, or a liquid nutritional supplement. Consume the drug/food mixture immediately without chewing; do not store for future use.

Dosage Modifications for Concomitant Use with CYP3A4 Inhibitors and Inducers

  • Coadministration with Strong CYP3A4 Inhibitors
    The recommended dose of NUPLAZID when coadministered with strong CYP3A4 inhibitors (e.g., ketoconazole) is 10 mg, taken orally as one tablet once daily [see Drug Interactions (7.1)].
  • Coadministration with Strong or Moderate CYP3A4 Inducers
    Avoid concomitant use of strong or moderate CYP3A4 inducers with NUPLAZID [see Drug Interactions (7.1)].
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