Drug Detail:Ofloxacin ophthalmic (Ofloxacin ophthalmic [ oh-flox-a-sin-off-thal-mik ])
Drug Class: Ophthalmic anti-infectives
Usual Adult Dose for Bacterial Conjunctivitis
Days 1 and 2: Instill 1 to 2 drops in the affected eye(s) every 2 to 4 hours.
Days 3 through 7: Instill 1 to 2 drops in the affected eye(s) 4 times a day.
Use: For the treatment of bacterial conjunctivitis due to susceptible strains of Staphylococcus aureus, S epidermidis, Streptococcus pneumoniae, Enterobacter cloacae, Haemophilus influenzae, Proteus mirabilis, Pseudomonas aeruginosa
Usual Adult Dose for Corneal Ulcers
Days 1 and 2: Instill 1 to 2 drops in the affected eye(s) every 30 minutes while awake and about 4 and 6 hours after retiring.
Days 3 through 7 to 9: Instill 1 to 2 drops in the affected eye(s) every hour while awake.
Days 7 to 9 through treatment completion: Instill 1 to 2 drops in the affected eye(s) 4 times a day.
Use: For the treatment of bacterial corneal ulcers due to susceptible strains of S aureus, S epidermidis, S pneumoniae, P aeruginosa, Serratia marcescens, Propionibacterium acnes
Usual Pediatric Dose for Bacterial Conjunctivitis
1 year or older:
- Days 1 and 2: Instill 1 to 2 drops in the affected eye(s) every 2 to 4 hours.
- Days 3 through 7: Instill 1 to 2 drops in the affected eye(s) 4 times a day.
Use: For the treatment of bacterial conjunctivitis due to susceptible strains of S aureus, S epidermidis, S pneumoniae, E cloacae, H influenzae, P mirabilis, P aeruginosa
Usual Pediatric Dose for Corneal Ulcers
1 year or older:
- Days 1 and 2: Instill 1 to 2 drops in the affected eye(s) every 30 minutes while awake and about 4 and 6 hours after retiring.
- Days 3 through 7 to 9: Instill 1 to 2 drops in the affected eye(s) every hour while awake.
- Days 7 to 9 through treatment completion: Instill 1 to 2 drops in the affected eye(s) 4 times a day.
Use: For the treatment of bacterial corneal ulcers due to susceptible strains of S aureus, S epidermidis, S pneumoniae, P aeruginosa, S marcescens, P acnes
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
Safety and efficacy have not been established in patients younger than 1 year.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- For topical ophthalmic use only (not for injection)
- Do not inject subconjunctivally; do not introduce directly into the anterior chamber of the eye.
- Consult the manufacturer product information for instillation instructions.
- If other topical ophthalmic agents are used, wait at least 10 minutes between instillations.
Patient advice:
- Do not wear contact lenses during therapy.
- Wash hands thoroughly before using this drug.
- Avoid contaminating the applicator tip with material from the eye, fingers, or any other source.
- Stop this drug and contact physician at first sign of rash or allergic reaction.
