Usual Adult Dose for Anxiety

10 to 15 mg orally, 3 or 4 times per day

Use: Management of mild-to-moderate anxiety, with associated tension, irritability, agitation, or related symptoms of functional origin or secondary to organic disease:

15 to 30 mg orally, 3 or 4 times per day

Use: Management of severe anxiety syndromes, agitation, or anxiety associated with depression

Usual Adult Dose for Alcohol Withdrawal

15 to 30 mg orally, 3 or 4 times per day

Use: Relief of symptoms in alcoholics with acute inebriation, tremulousness, or anxiety on withdrawal

Usual Geriatric Dose for Anxiety

10 mg orally, 3 times per day; if needed, increase cautiously to 15 mg orally, 3 or 4 times per day

Use: Management of anxiety, tension, irritability, and agitation in older patients

Usual Pediatric Dose for Anxiety

13 years and older:
10 to 15 mg orally, 3 or 4 times per day

Comments:

• The absolute dosage for patients 6 to 12 years is not established.

• The absolute dosage for patients 6 to 12 years is not established.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

• Dose adjustments may be required when this drug is used concomitantly with alcohol or other CNS-acting drugs.

Precautions

Safety and efficacy have not been established in patients younger than 6 years.

Consult WARNINGS section for additional precautions.

US Controlled Substance: Schedule IV

Dialysis

Data not available

Other Comments

Monitoring:

• Psychiatric: Patients with a history of alcohol or drug abuse, or patients with a marked personality disorder should be monitored frequently.

• General: Patients should be aware of the possibility of rebound phenomena.