The recommended dose for Reltone™ treatment of radiolucent gallbladder stones is 8-10 mg/kg/day given in 2 or 3 divided doses.
Ultrasound images of the gallbladder should be obtained at 6-month intervals for the first year of Reltone™ therapy to monitor gallstone response. If gallstones appear to have dissolved, Reltone™ therapy should be continued and dissolution confirmed on a repeat ultrasound examination within 1 to 3 months. Most patients who eventually achieve complete stone dissolution will show partial or complete dissolution at the first on-treatment reevaluation. If partial stone dissolution is not seen by 12 months of Reltone™ therapy, the likelihood of success is greatly reduced.
Gallstone Prevention
The recommended dosage of Reltone™ for gallstone prevention in patients undergoing rapid weight loss is 600 mg/day.
