Drug Detail:Retapamulin topical (Retapamulin topical [ re-te-pam-ue-lin ])
Drug Class: Topical antibiotics
Usual Adult Dose for Impetigo
Apply a thin layer to the affected area (up to 100 cm2 in total area) twice a day for 5 days
Comments:
- Consider alternative therapy if there is no improvement or worsening in the affected area after 2 to 3 days of treatment.
Use: Topical treatment of impetigo due to methicillin-susceptible Staphylococcus aureus or Streptococcus pyogenes
Usual Pediatric Dose for Impetigo
Apply a thin layer to the affected area (up to 2% total body surface area) twice a day for 5 days
Comments:
- For pediatric patients aged 9 months or older.
- Concomitant use with strong CYP450 3A4 inhibitors is not recommended in patients younger than 24 months of age due to the higher systemic exposure of the drug in this patient population.
- Consider alternative therapy if there is no improvement or worsening in the affected area after 2 to 3 days of treatment.
Use: Topical treatment of impetigo due to methicillin-susceptible Staphylococcus aureus or Streptococcus pyogenes
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
Safety and efficacy have not been established in patients younger than 9 months.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- The treated area may be covered by a sterile bandage or gauze dressing.
- Concomitant use with other topical medicinal products to the same affected area has not been studied and is not recommended.
Patient advice:
- Wash your hands before and after use.
- Clean and dry the affected area before use.
- Put a thin layer on the affected area and rub in gently.
- Use on your skin only. Do not take this drug by mouth and keep it out of your eyes, nose, and genital area.
- Contact your doctor if the treated area worsens in irritation, redness, itching, burning, swelling, blistering, or oozing.
