Metastatic Breast Cancer

For patients with breast cancer, the recommended daily dose of SOLTAMOX is 20 to 40 mg. Doses greater than 20 mg per day should be given in divided doses (morning and evening).

Adjuvant Treatment of Breast Cancer

For use in the adjuvant setting, the recommended dose of SOLTAMOX is 20 mg daily for 5-10 years [see Clinical Studies (14.2)]. Doses greater than 20 mg daily yield no additional clinical benefit.

Ductal Carcinoma in Situ

For patients with DCIS, the recommended dose of SOLTAMOX is 20 mg daily for 5 years.

Reduction in Breast Cancer Incidence in Women at High Risk

In the risk reduction setting, the recommended dose of SOLTAMOX is 20 mg daily for 5 years.