Usual Adult Dose for Acne

Apply a thin layer to the affected areas once a day (in the evening) on clean and dry skin.

Comments:

• One pump actuation should be enough to cover the face (i.e., forehead, cheeks, nose, chin).
• Two actuations of the pump should be enough to cover the upper trunk (i.e., reachable upper back, shoulders, chest); if needed, use 1 additional pump actuation for acne on the middle and lower back.
• Moisturizer should be used as often as needed from the start of therapy.

Usual Pediatric Dose for Acne

9 years or older: Apply a thin layer to the affected areas once a day (in the evening) on clean and dry skin.

Comments:

• One pump actuation should be enough to cover the face (i.e., forehead, cheeks, nose, chin).
• Two actuations of the pump should be enough to cover the upper trunk (i.e., reachable upper back, shoulders, chest); if needed, use 1 additional pump actuation for acne on the middle and lower back.
• Moisturizer should be used as often as needed from the start of therapy.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS: None

Safety and efficacy have not been established in patients younger than 9 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Prime pump for the first time by pressing down several times until a small amount of medicine is dispensed.
• For topical use only; not for oral, ophthalmic, or intravaginal use.
• Avoid contact with the eyes, lips, paranasal creases, mucous membranes.

• Store at 20C to 25C (68F to 77F); excursions permitted to 15C to 30C (59F to 86F).
• Keep away from heat.

• Read the US FDA-approved patient labeling (Patient Information).
• Cleanse the area to be treated and pat dry; apply a thin layer to the face, avoiding the eyes, lips, nasolabial folds, and mucous membranes; may also apply a thin layer to the chest, shoulders, and back.
• Do not apply to damaged skin (e.g., cuts, abrasions), eczematous areas, and sunburned skin.
• Reduce the risk of skin irritation: Use a moisturizer from the start of therapy; if appropriate, reduce the frequency of application or suspend use temporarily.
• Minimize exposure to sunlight (including sunlamps, phototherapy devices); use sunscreen products and protective apparel (e.g., hat) over treated areas when sun exposure cannot be avoided.
• Avoid concurrent use of other potentially irritating topical products (medicated or not).
• While breastfeeding: Use on the smallest area of skin for the shortest duration possible; do not apply this drug directly to nipple and areola (to avoid direct infant exposure).
• If the drug enters the eye, wash immediately and abundantly with lukewarm water.