Bile acid sequestrants
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Welchol Dosage

Drug Detail:Welchol (Colesevelam [ koe-le-sev-e-lam ])

Generic Name: COLESEVELAM HYDROCHLORIDE 625mg

Dosage Form: tablet, film coated, oral suspension

Drug Class: Bile acid sequestrants

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

Testing Prior to Initiation of WELCHOL

Obtain lipid parameters, including triglyceride (TG) levels, before starting WELCHOL. WELCHOL is contraindicated in patients with TG levels >500 mg/dL [see Contraindications (4) and Warnings and Precautions (5.1)].

Recommended Dosage in Primary Hyperlipidemia and Type 2 Diabetes Mellitus

The recommended dosage of WELCHOL for adults and for boys and postmenarchal girls aged 10 to 17 years with primary hyperlipidemia is 3.75 grams daily. The recommended dosage of WELCHOL for adults with type 2 diabetes mellitus is 3.75 grams daily. WELCHOL should be taken as follows:

Tablets

Take 6 tablets once daily or 3 tablets twice daily. Due to tablet size, WELCHOL for oral suspension is recommended for use in the pediatric population.

For Oral Suspension

Take one packet once daily.

Important Dosing Information for Primary Hyperlipidemia

WELCHOL can be dosed at the same time as a statin, or WELCHOL and the statin can be dosed apart. Monitor lipid levels within 4 to 6 weeks after initiation of WELCHOL.

Administration Instructions

Tablets

Take WELCHOL tablets with a meal and liquid. For patients with difficulty swallowing tablets, use WELCHOL for oral suspension [see Warnings and Precautions (5.2)].

For Oral Suspension

To prepare, empty the entire contents of one packet into a glass or cup. Add 1 cup (8 ounces) of water, fruit juice, or diet soft drinks. Stir well and drink. Take WELCHOL oral suspension with meals. Do not take WELCHOL oral suspension in its dry form. Due to tablet size, WELCHOL for oral suspension is recommended for use in the pediatric population.

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