Latest Drugs, Latest Approval in Antidotes

What are Antidotes?

An antidote is a drug, chelating substance, or a chemical that counteracts (neutralizes) the effects of another drug or a poison.

There are dozens of different antidotes; however, some may only counteract one particular drug, whereas others (such as charcoal) may help reduce the toxicity of numerous drugs. Most antidotes are not 100% effective, and fatalities may still occur even when an antidote has been given. Some examples of antidotes include:

  • Acetylcysteine for acetaminophen poisoning
  • Activated charcoal for most poisons
  • Atropine for organophosphates and carbamates
  • Digoxin immune fab for digoxin toxicity
  • Dimercaprol for arsenic, gold, or inorganic mercury poisoning
  • Flumazenil for benzodiazepine overdose
  • Methylene blue for drug-induced methemoglobinemia
  • Naloxone for opioid overdose
  • Pralidoxime for poisoning by anti-cholinesterase nerve agents.

Name Updated
Kloxxado (Naloxone (nasal) [ na-lox-one ]) 04-Oct-2023
Evzio (Naloxone [ nah-lox-one ]) 29-Aug-2023
Narcan (Naloxone) 21-Aug-2023
Naloxone (Naloxone [ nah-lox-one ]) 21-Aug-2023
Narcan (injection) (Naloxone (injection) [ nah-lox-one ]) 17-Aug-2023
Methylene blue (injection) (Methylene blue (injection) [ meth-i-leen-bloo ]) 17-Aug-2023
Flumazenil (Flumazenil [ floo-maz-e-nil ]) 16-Aug-2023
Levoleucovorin (Levoleucovorin [ lee-voe-loo-koe-voe-rin ]) 16-Aug-2023
Leucovorin (injection) (Leucovorin (injection) [ loo-koe-vor-in ]) 15-Aug-2023
Pentetate (Pentetate calcium trisodium (systemic)) 15-Aug-2023
Naltrexone (injection) (Naltrexone (injection) [ nal-trex-own ]) 15-Aug-2023
Naloxone (nasal) (Naloxone (nasal) [ na-lox-one ]) 15-Aug-2023
Leucovorin (Leucovorin (oral) [ loo-koe-vor-in ]) 14-Aug-2023
Glucarpidase (Glucarpidase [ gloo-kar-pi-dase ]) 14-Aug-2023
Fomepizole (Fomepizole [ foe-mep-i-zole ]) 14-Aug-2023
Deferoxamine (Deferoxamine [ de-fer-ox-a-meen ]) 14-Aug-2023
Deferiprone (Deferiprone [ de-fer-i-prone ]) 14-Aug-2023
Sodium nitrite and sodium thiosulfate (Sodium nitrite and sodium thiosulfate [ soo-dee-um-nye-trite-and-soo-de-um-thye-oh-sul-fate ]) 14-Aug-2023
Physostigmine (Physostigmine [ fye-so-stig-meen ]) 14-Aug-2023
Dimercaprol (Dimercaprol [ dye-mer-kap-rol ]) 13-Aug-2023
Digoxin immune fab (Digoxin immune fab [ di-jox-in-im-myoon-fab ]) 13-Aug-2023
Atropine (injection) (Atropine (injection) [ at-roe-peen ]) 13-Aug-2023
Atropine and pralidoxime (Atropine and pralidoxime [ at-roe-peen-and-pral-i-dox-eem ]) 13-Aug-2023
Acetylcysteine (inhalation) (Acetylcysteine (inhalation) [ a-seet-il-sis-teen ]) 13-Aug-2023
Uridine triacetate (Uridine triacetate [ ure-i-deen-trye-as-e-tate ]) 12-Aug-2023
Prussian blue (Prussian blue [ prush-an-bloo ]) 12-Aug-2023
Pralidoxime (Pralidoxime [ pral-i-dox-eem ]) 12-Aug-2023
Naltrexone (Naltrexone, naltrexone hydrochloride) 11-Aug-2023
Naloxone (Naloxone [ nah-lox-one ]) 11-Aug-2023
Edetate calcium disodium (Edetate calcium disodium [ ed-e-tate-kal-see-um-dye-soe-dee-um ]) 11-Aug-2023
Zimhi (injection) (Naloxone (injection) [ nah-lox-one ]) 07-Aug-2023
Provayblue (injection) (Methylene blue (injection) [ meth-i-leen-bloo ]) 06-Aug-2023
Actidose-aqua (Activated charcoal [ char-coal ]) 05-Aug-2023
Protopam chloride (Pralidoxime [ pral-i-dox-eem ]) 05-Aug-2023
Activated charcoal (Activated charcoal [ char-coal ]) 05-Aug-2023
Antizol (Fomepizole [ foe-mep-i-zole ]) 05-Aug-2023
Antilirium (Physostigmine [ fye-so-stig-meen ]) 05-Aug-2023
Acetadote (Acetylcysteine injection) 05-Aug-2023
Kloxxado (Naloxone (nasal) [ na-lox-one ]) 05-Aug-2023
Charcocaps (Activated charcoal [ char-coal ]) 05-Aug-2023
Char-flo aqueous base (Activated charcoal [ char-coal ]) 04-Aug-2023
Rivive (Naloxone) 01-Aug-2023
Zimhi (Naloxone hydrochloride) 14-Jul-2023
Voraxaze (Glucarpidase [ gloo-kar-pi-dase ]) 14-Jul-2023
Vistogard (Uridine triacetate [ ure-i-deen-trye-as-e-tate ]) 14-Jul-2023
Revia (Naltrexone (oral) [ nal-trex-own ]) 14-Jul-2023
Radiogardase (Prussian blue [ prush-an-bloo ]) 14-Jul-2023
Opvee (Nalmefene) 13-Jul-2023
Optimum charcoal (Activated charcoal [ char-coal ]) 13-Jul-2023
Nithiodote (Sodium nitrite and sodium thiosulfate [ soo-dee-um-nye-trite-and-soo-de-um-thye-oh-sul-fate ]) 13-Jul-2023