Interferons are proteins produced by tumor cells or host cells that are infected with viruses, bacteria and other unknown nucleic acids. Interferons also activate other cells that serve as part of the immune system and destroy invading pathogens.
Interferons are classed as: alpha (from white cells), beta (from fibroblasts) and gamma (from lymphocytes). Interferons enhance the immune system in many ways so can be used to treat different conditions involving the immune system.
Interferons used therapeutically are manufactured using recombinant DNA technology.
Interferon alphas are used to treat viral infections (chronic hepatitis, human papillomavirus) and treating cancer (hairy cell leukemia, AIDS related - Kaposi sarcoma, malignant melanoma).
Interferon betas are used to treat or slow down the progression of multiple sclerosis.
Interferon gamma is used to treat chronic granulomatous disease.
